Changes of the intensity of light reflected or passing through cuvette with the blood specify the degree of blood aggregation. The parameters of light reflection by the surface of blood in macro-cuvette are compared with those of light passage through a thin micro-cuvette with preliminarily stirred blood. The latter technique enables a direct microscopy of the erythrocytes aggregation. Virtually similar results were obtained with blood of different animals and with different values of hematocrit. The data suggest a correlation between velocity of the aggregation and increase of the hematocrit value. Causes of discrepancies of the absolute values of parameters under study are discussed.
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Haematologica
January 2025
Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam.
Not available.
View Article and Find Full Text PDFHaematologica
January 2025
Clinical Hematology, Nantes University Hospital, Nantes.
Not available.
View Article and Find Full Text PDFInotuzumab ozogamicin (InO) is approved for treatment of relapsed/refractory acute lymphoblastic leukemia (R/R ALL). Previous studies reported higher rates of post- hematopoietic stem cell transplant (HSCT) hepatic sinusoidal obstruction syndrome (SOS) in patients receiving InO versus chemotherapy prior to HSCT. It is unknown if a lower InO dose would reduce risk of post-HSCT SOS or if it would impact efficacy.
View Article and Find Full Text PDFSpine (Phila Pa 1976)
January 2025
Department of Orthopaedics, All India Institute of Medical Sciences, Rishikesh, India.
Study Design: Systematic review and meta analysis.
Objective: To assess the safety and efficacy of staged versus same-day spinal fusion surgeries in Adult spinal deformity (ASD).
Background: ASD surgeries are associated with high complication rates, ranging from 10% to 40%.
Dis Model Mech
January 2025
Divisions of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Gsx2 is a homeodomain transcription factor critical for development of the ventral telencephalon and hindbrain of the mouse. Loss of Gsx2 function results in severe basal ganglia dysgenesis as well as defects in the nucleus tractus solitarius (nTS) of the hindbrain together with respiratory failure at birth. De Mori et al.
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