AI Article Synopsis

  • * A case study of an 83-year-old male reveals that he experienced cold sweats shortly after his first COVID-19 vaccine and subsequently suffered an AMI the next day, which was linked to coronary thrombosis and underlying heart disease.
  • * The study suggests that Type II Kounis syndrome, an allergic reaction leading to coronary issues, could explain AMI occurrences post-vaccination and emphasizes the importance of clinicians being aware of such risks and their mechanisms.

Article Abstract

A number of vaccines have been developed and deployed globally to restrain the spreading of the coronavirus disease 2019 (COVID-19). The adverse effect following vaccination is an important consideration. Acute myocardial infarction (AMI) is a kind of rare adverse event after COVID-19 vaccination. Herein, we present a case of an 83-year-old male who suffered cold sweat ten minutes after the first inactivated COVID-19 vaccination and AMI one day later. The emergency coronary angiography showed coronary thrombosis and underlying stenosis in his coronary artery. Type II Kounis syndrome might be a potential mechanism, which is manifested as coronary thrombosis secondary to allergic reactions in patients with underlying asymptomatic coronary heart disease. We also summarize the reported AMI cases post COVID-19 vaccination, as well as overview and discuss the proposed mechanisms of AMI after COVID-19 vaccination, thus providing insights for clinicians to be aware of the possibility of AMI following COVID-19 vaccination and potential underlying mechanisms.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262047PMC
http://dx.doi.org/10.3389/fcvm.2023.1123385DOI Listing

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