AI Article Synopsis
- ADP-ribosylation is a crucial process that modifies proteins after translation and plays a key role in repairing DNA.
- Researchers led by Longarini studied the specifics of ADP-ribosylation dynamics, uncovering important details about its different forms.
- Their findings highlight how these forms of ADP-ribosylation control when DNA repair happens in response to strand breaks.
Article Abstract
ADP-ribosylation is a complex post-translation modification involved in DNA repair. In a recent publication, Longarini and colleagues measured ADP-ribosylation dynamics with unprecedented specificity, revealing how the monomeric and polymeric forms of ADP-ribosylation regulate the timing of DNA repair events following strand breaks.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261921 | PMC |
| http://dx.doi.org/10.1016/j.crmeth.2023.100484 | DOI Listing |
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