Direct oral anticoagulants (DOACs) are well known to be associated with bleeding complications. However, little is known about their association with atraumatic splenic rupture, a potentially fatal condition. We present the case of a 73-year-old female with paroxysmal atrial fibrillation managed with rivaroxaban who developed a spontaneous atraumatic splenic rupture. This highlights the importance of recognizing this complication in patients without previous risk factors, such as abdominal trauma or infiltrative splenic disease, who are under anticoagulation with DOACs. There is a strong need for further research on this complication's underlying mechanism and management.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262104PMC
http://dx.doi.org/10.7759/cureus.38992DOI Listing

Publication Analysis

Top Keywords

atraumatic splenic
12
splenic rupture
12
rupture notable
4
notable complication
4
complication rivaroxaban
4
rivaroxaban direct
4
direct oral
4
oral anticoagulants
4
anticoagulants doacs
4
doacs well
4

Similar Publications

[Atraumatic splenic rupture in Legionella pneumonia].

Inn Med (Heidelb)

December 2024

Klinik für Innere Medizin, Rheumatologie, Pneumologie, Nephrologie und Diabetologie, medius Klinik Kirchheim, Kirchheim unter Teck, Deutschland.

A 48-year-old male patient was admitted to hospital with Legionella pneumonia. He developed a splenic rupture 1 day after admission, which was surgically treated. Retrospectively, the splenomegaly could already be seen by sonography on admission.

View Article and Find Full Text PDF

Differences in Management and Outcomes in Atraumatic Splenic Rupture Compared to Traumatic Injury Following Blunt Abdominal Trauma.

J Clin Med

December 2024

Diagnostic and Interventional Radiology, University Hospital Augsburg, Faculty of Medicine, University of Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany.

: To evaluate the differences in treatment and outcomes between traumatic and atraumatic splenic lacerations. : This retrospective study included all patients with a diagnosis of splenic lacerations confirmed by computed tomography that presented from 01/2010 to 03/2023 at one tertiary hospital. The exclusion criteria included missing image data and death in the first 24 h due to extensive trauma.

View Article and Find Full Text PDF

A Rare Complication of Atraumatic Splenic Rupture in Infectious Mononucleosis: A Case Report.

Br J Hosp Med (Lond)

November 2024

Department of Surgery, General Hospital of Syros, "Vardakeio and Proïo", Hermoupolis, Syros, Greece.

Atraumatic splenic rupture is a very rare and potentially life-threatening event usually associated with underlying pathological conditions. Splenic rupture in infectious mononucleosis occurs only in 0.1%-0.

View Article and Find Full Text PDF

Atraumatic splenic rupture (ASR) is an unfamiliar entity that is potentially life-threatening if there is a delay in the diagnosis. Due to its rarity and its non-specific presentation, it can be a challenge to diagnose early. In this report, we present a case of a 42-year-old male patient who presented to the emergency department with nonspecific abdominal pain and had no past medical history.

View Article and Find Full Text PDF

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a rare hematologic cancer, accounting for less than 1% of acute leukemias in the U.S. Diagnosis involves detecting markers like CD123, CD4, CD56, TCL1, and TCF4.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!