Direct oral anticoagulants (DOACs) are well known to be associated with bleeding complications. However, little is known about their association with atraumatic splenic rupture, a potentially fatal condition. We present the case of a 73-year-old female with paroxysmal atrial fibrillation managed with rivaroxaban who developed a spontaneous atraumatic splenic rupture. This highlights the importance of recognizing this complication in patients without previous risk factors, such as abdominal trauma or infiltrative splenic disease, who are under anticoagulation with DOACs. There is a strong need for further research on this complication's underlying mechanism and management.
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http://dx.doi.org/10.7759/cureus.38992 | DOI Listing |
Inn Med (Heidelb)
December 2024
Klinik für Innere Medizin, Rheumatologie, Pneumologie, Nephrologie und Diabetologie, medius Klinik Kirchheim, Kirchheim unter Teck, Deutschland.
A 48-year-old male patient was admitted to hospital with Legionella pneumonia. He developed a splenic rupture 1 day after admission, which was surgically treated. Retrospectively, the splenomegaly could already be seen by sonography on admission.
View Article and Find Full Text PDFJ Clin Med
December 2024
Diagnostic and Interventional Radiology, University Hospital Augsburg, Faculty of Medicine, University of Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany.
: To evaluate the differences in treatment and outcomes between traumatic and atraumatic splenic lacerations. : This retrospective study included all patients with a diagnosis of splenic lacerations confirmed by computed tomography that presented from 01/2010 to 03/2023 at one tertiary hospital. The exclusion criteria included missing image data and death in the first 24 h due to extensive trauma.
View Article and Find Full Text PDFBr J Hosp Med (Lond)
November 2024
Department of Surgery, General Hospital of Syros, "Vardakeio and Proïo", Hermoupolis, Syros, Greece.
Atraumatic splenic rupture is a very rare and potentially life-threatening event usually associated with underlying pathological conditions. Splenic rupture in infectious mononucleosis occurs only in 0.1%-0.
View Article and Find Full Text PDFCureus
October 2024
Emergency Medicine, Southern Health and Social Care Trust, Craigavon, GBR.
Atraumatic splenic rupture (ASR) is an unfamiliar entity that is potentially life-threatening if there is a delay in the diagnosis. Due to its rarity and its non-specific presentation, it can be a challenge to diagnose early. In this report, we present a case of a 42-year-old male patient who presented to the emergency department with nonspecific abdominal pain and had no past medical history.
View Article and Find Full Text PDFJ Community Hosp Intern Med Perspect
September 2024
Allegheny General Hospital, Department of Hematology & Oncology, Pittsburgh, PA, USA.
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a rare hematologic cancer, accounting for less than 1% of acute leukemias in the U.S. Diagnosis involves detecting markers like CD123, CD4, CD56, TCL1, and TCF4.
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