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MAIT cells modulating the oral lichen planus immune microenvironment: a cellular crosstalk perspective.
Inflamm Res
January 2025
Departments of Oral Medicine, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong Province, China.
Mucosal-associated invariant T (MAIT) cells, a type of T lymphocytes with innate-like characteristics, are crucial in bridging innate and adaptive immunity. When activated, MAIT cells release various inflammatory molecules and swiftly respond to antigens. Notably, numerous studies highlight the significant impact of MAIT cells on tumors and various immune disorders by influencing the immune microenvironment.
View Article and Find Full Text PDF"Comparison of the efficacy of Erich arch bars, IMF screws and SMART Lock Hybrid arch bars in the management of mandibular fractures- A Randomized clinical study".
J Stomatol Oral Maxillofac Surg
January 2025
Department of Dentistry, Arundhati Institute of Medical Sciences, Telangana, India.
Purpose: The purpose of this study was to assess and compare the efficacy of Erich Arch Bar (EAB), Inter Maxillary Fixation (IMF) screws and SMART Lock Hybrid arch bar (HABs) in the treatment of mandibular fractures.
Materials And Methods: A prospective randomized clinical study was carried out in the Department of Dentistry at ESIC Hospital in Hyderabad from August 2021 to August 2023. The study comprised of three groups (EAB group (31), IMF screw group (33) and HABs group (29)).
Investigating Oral Cancer Awareness Among Medical and Dental Students: A Cross-Sectional Study in the South Canara Region of India.
ScientificWorldJournal
January 2025
Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Oral cancer is responsible for increased mortality, especially in the Indian subcontinent. Habits like smoking and tobacco chewing are among the most common causes of oral cancer. Previously, these habits were seen mainly in the elderly; however, the trends have seemed to increase in the younger generation.
View Article and Find Full Text PDFVulvo-Vaginal-Oral Lichen Planus: A Case Report and Literature Review.
Cureus
December 2024
Oral Medicine and Diagnostic Science, College of Dentistry, King Saud University, Riyadh, SAU.
Vulvo-vaginal-oral lichen planus (VVO-LP) is a chronic inflammatory condition affecting the mucous membranes of the oral cavity, skin, and genital areas. The exact etiology remains unclear, although immune-mediated mechanisms are considered likely contributors. It is a rare form of lichen planus, which typically presents in adults and is more common in middle-aged women.
View Article and Find Full Text PDFCalcium channels as therapeutic targets in head and neck squamous cell carcinoma: current evidence and clinical trials.
Front Oncol
December 2024
Department of Otolaryngology, Longgang Otolaryngology hospital & Shenzhen Key Laboratory of Otolaryngology, Shenzhen Institute of Otolaryngology, Shenzhen, China.
Head and neck squamous cell carcinoma (HNSCC) originates from the mucosal epithelium of the oral cavity, pharynx, and larynx, and is marked by high rates of recurrence and metastasis. Calcium signaling is associated with the progression of HNSCC and the development of drug resistance. Changes in calcium ion flow can trigger severe pathophysiological processes, including malignant transformation, tumor proliferation, epithelial-mesenchymal transition, and apoptosis evasion.
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