Bioengineering of bacteria for cancer immunotherapy.

Nat Commun

Institute for Molecular Imaging and Theranostics, Department of Nuclear Medicine, Chonnam National University Medical School and Hospital, Gwangju, 61469, Republic of Korea.

Published: June 2023

Here, we provide a brief overview of the approaches and strategies underlying bacteria-based cancer immunotherapy (BCiT). We also describe and summarize research in the field of synthetic biology, which aims to regulate bacterial growth and gene expression for immunotherapeutic use. Finally, we discuss the current clinical status and limitations of BCiT.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272223PMC
http://dx.doi.org/10.1038/s41467-023-39224-8DOI Listing

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