Background: Traditionally, functional neurosurgery relied in stereotactic atlases and intraoperative micro-registration in awake patients for electrode placement in Parkinson's disease. Cumulative experience on target description, refinement of MRI, and advances in intraoperative imaging has enabled accurate preoperative planning and its implementation with the patient under general anaesthesia.

Methods: Stepwise description, emphasising preoperative planning, and intraoperative imaging verification, for transition to asleep-DBS surgery.

Conclusion: Direct targeting relies on MRI anatomic landmarks and accounts for interpersonal variability. Indeed, the asleep procedure precludes patient distress. A particular complication to avoid is pneumocephalus; it can lead to brain-shift and potential deviation of electrode trajectory.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409652PMC
http://dx.doi.org/10.1007/s00701-023-05659-7DOI Listing

Publication Analysis

Top Keywords

placement parkinson's
8
parkinson's disease
8
intraoperative imaging
8
preoperative planning
8
asleep dbs
4
dbs placement
4
disease background
4
background traditionally
4
traditionally functional
4
functional neurosurgery
4

Similar Publications

Background: Andersen-Tawil syndrome (ATS) is a rare autosomal dominant disorder caused by variants in the gene. It is associated with periodic paralysis, dysmorphic features and cardiac arrhythmias. The syndrome exhibits incomplete penetrance, leading to a broad spectrum of clinical manifestations, making diagnosis challenging.

View Article and Find Full Text PDF

Redefining Ventricular Access Landmarks: A Novel Approach Using Magnetic Resonance Imaging and 3-Dimensional Reconstructions for Keen's Point Trajectories.

World Neurosurg

December 2024

Functional Neurosurgery Research Center, Research Institute of Functional Neurosurgery, Shohada Tajrish Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

Background: Cerebrospinal fluid diversion via shunt placement is a common neurosurgical intervention. Keen's Point is a widely used landmark for accessing the trigone of the lateral ventricle; however, it lacks clinical validation. This study re-evaluates Keen's Point scalp parameters using magnetic resonance imaging (MRI) to identify an ideal shunt entry point based on 3-dimensional reconstructions.

View Article and Find Full Text PDF

Background: Parkinson's disease psychosis (PDPsy) is associated with increased nursing home placement and mortality and is closely linked with cognitive dysfunction.

Objective: Assess the clinical and cognitive features associated with PDPsy in patients without dementia.

Methods: We prospectively recruited people with Parkinson's disease (PwP) without dementia for a 3-year, longitudinal study at an outpatient movement disorders clinic.

View Article and Find Full Text PDF

Long-term Survival of Bladder Augmentation is Influenced by its Shape and Mucosal Lining.

J Pediatr Surg

November 2024

Department of Paediatric Surgery and Urology, Birmingham Children's Hospital, Steelhouse Lane, Queensway, Birmingham B4 6NH, UK. Electronic address:

Introduction: Bladder augmentation in the UK has been largely by enterocystoplasty or ureterocystoplasty (UC). Ileocystoplasty can be simple patch placement (SPP), or formation of an ileal cup (IC). Urothelium is the "right" mucosa, whereas intestinal mucosa exhibits absorption, mucus production, malignancy.

View Article and Find Full Text PDF

In 2017 a novel growth factor administration therapy (termed NTCELL®) was trialled for safety and efficacy for Parkinson's disease treatment. NTCELL® administration is the transplantation of encapsulated porcine choroid plexus cells into the putamen. A clinical study demonstrated safety but failed to meet its primary clinical end-point.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!