AI Article Synopsis

  • * The classic symptoms include muscle pain, weakness, and dark urine, but only occur in about 10% of cases, making imaging important for assessing muscle damage and potential complications.
  • * Imaging techniques like MRI, CT, ultrasound, and 18-FDG PET/CT are crucial for evaluating the severity of rhabdomyolysis and detecting related issues such as myonecrosis, muscular atrophy, or other injuries, especially in trauma situations.

Article Abstract

This review illustrates the imaging features of rhabdomyolysis across multiple modalities and in a variety of clinical scenarios. Rhabdomyolysis is the rapid breakdown of striated muscle following severe or prolonged insult resulting in the release of myocyte constituents into circulation. In turn, patients develop characteristically elevated serum creatine kinase, positive urine myoglobin, and other serum and urine laboratory derangements. While there is a spectrum of clinical symptoms, the classic presentation has been described as muscular pain, weakness, and dark urine. This triad, however, is only seen in about 10% of patients. Thus, when there is a high clinical suspicion, imaging can be valuable in evaluating the extent of muscular involvement, subsequent complications such as myonecrosis and muscular atrophy, and other etiologies or concurrent injuries causing musculoskeletal swelling and pain, especially in the setting of trauma. Sequela of rhabdomyolysis can be limb or life-threatening including compartment syndrome, renal failure, and disseminated intravascular coagulation. MRI, CT, ultrasound, and 18-FDG PET/CT are useful modalities in the evaluation of rhabdomyolysis.

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Source
http://dx.doi.org/10.1007/s00256-023-04378-5DOI Listing

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