is a difficult-to-treat pathogen that is frequently involved with chronic wound infections. Here, we conducted a literature search of world-wide studies published between 2005 and 2022 that described the microbiological profiles of chronic wound infections. For each continent, a hierarchy of pathogens was created to define the organisms that were most frequently isolated in each region. Except for South America, was the second most common organism in each major continent, with being the most abundant pathogen overall. When individual countries were evaluated, was the most frequently isolated organism in several Southeast Asia nations including India and Malaysia. was less commonly isolated from diabetic foot infections in North America, Europe, and Africa in comparison to other types of chronic wound infections. Additionally, the Levine wound swab technique may be a quick and painless way to isolate from wound infections, but the isolation of does not seem to be an informative predictor of the patient's clinical course. A multivariate risk assessment that accounts for the regional frequency of isolation may be an appropriate way to guide empiric management of chronic wound infections.
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http://dx.doi.org/10.3390/microorganisms11051210 | DOI Listing |
Sci Rep
December 2024
Consumer and Design Sciences, College of Human Science Auburn University, Auburn, Alabama, USA.
Bermuda grass (Cynodon dactylon) is a tropical grass found in all tropical and subtropical areas. It is widely found in Bangladesh and well known for its antimicrobial properties. Cotton gauze is a woven cloth which is used for wound dressing and wound cushioning.
View Article and Find Full Text PDFJ Biomed Mater Res B Appl Biomater
January 2025
Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
IntroductionProlonged hyperglycemia in diabetic patients often impairs wound healing, leading to chronic infections and complications. This study aimed to evaluate the potential of fresh Tilapia fish skin as a treatment to enhance wound healing in diabetic rats. MethodsThirty-nine healthy adult albino rats, weighing between 150 and 200 g, were divided into three groups: non-diabetic rats with untreated wounds [C-], diabetic rats with untreated wounds [C+], and diabetic rats treated with fresh Tilapia skin [TT].
View Article and Find Full Text PDFWound Repair Regen
December 2024
Department of Dermatology, University of California Davis School of Medicine, Sacramento, California, USA.
Bacterial biofilms represent a formidable challenge in the treatment of chronic wounds, largely because of their resistance to conventional antibiotics. The emergence of multidrug-resistant (MDR) bacterial strains exacerbates this issue, necessitating a shift towards exploring alternative therapeutic approaches. In response to this urgent need, there has been a surge in research efforts aimed at identifying effective non-antibiotic treatments.
View Article and Find Full Text PDFIndian J Med Res
November 2024
Department of Laboratory Medicine, Jai Prakash Narayan Apex Trauma Center, All India Institute of Medical Sciences, New Delhi, India.
Background & objectives Surgical site infections (SSIs) are among the most prevalent healthcare-associated infections (HCAIs). They cause significant morbidity, leading to excess health expenditures and increased length of hospital stay. Despite a high population burden, data on post-discharge SSIs is lacking from low-and middle-income countries (LMICs).
View Article and Find Full Text PDFCytojournal
November 2024
Department of Hand and Foot Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Qingdao, China.
Objective: Rheumatoid arthritis (RA) is a disabling systemic autoimmune disease worldwide; however, its molecular pathway remains largely unknown. Thus, this study aimed to explore the effects of receptor-interacting serine/threonine kinase 2 (RIPK2) on RA progression and its underlying mechanism.
Material And Methods: RIPK2 expression was analyzed using real-time quantitative polymerase chain reaction, immunohistochemical staining, and Western blot (WB) analysis in RA synovial tissues or cells.
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