Microfluidics: Insights into Intestinal Microorganisms.

Microorganisms

The First Clinical Medical College, Lanzhou University, Lanzhou 730000, China.

Published: April 2023

Microfluidics is a system involving the treatment or manipulation of microscale (10 to 10 L) fluids using microchannels (10 to 100 μm) contained on a microfluidic chip. Among the different methodologies used to study intestinal microorganisms, new methods based on microfluidic technology have been receiving increasing attention in recent years. The intestinal tracts of animals are populated by a vast array of microorganisms that have been established to play diverse functional roles beneficial to host physiology. This review is the first comprehensive coverage of the application of microfluidics technology in intestinal microbial research. In this review, we present a brief history of microfluidics technology and describe its applications in gut microbiome research, with a specific emphasis on the microfluidic technology-based intestine-on-a-chip, and also discuss the advantages and application prospects of microfluidic drug delivery systems in intestinal microbial research.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223655PMC
http://dx.doi.org/10.3390/microorganisms11051134DOI Listing

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