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Endophenotype presentation of athletes with concussion contingent on sex and time since injury.
Brain Inj
January 2025
Department of Sports Medicine, Texas Scottish Rite Hospital for Children, Dallas, Texas, USA.
Introduction: Athletes with concussions experience heterogeneous symptoms and clinical trajectories. Subclassification provides diagnostic clarity that may improve prognostication and individualized treatments.
Methods: We hypothesized that endophenotypes of adolescent athletes with concussions differ based on sex and time since injury.
Risk factor, neuropathological, and clinical correlates of perivascular spaces in brain donors exposed to repetitive head impacts.
Alzheimers Dement
December 2024
Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA
Background: Enlarged perivascular spaces (ePVS) on MRI can signal impaired cerebral fluid clearance and predict dementia risk. Risk factors and biological correlates of ePVS are uncertain partially due to the lack of pathological correlation studies. Repetitive head impacts (RHI) from contact sports might represent one risk factor for ePVS, given their association with vascular pathologies and chronic traumatic encephalopathy (CTE), a neurodegenerative disease characterized by perivascular p‐tau aggregates.
View Article and Find Full Text PDFthe diagnostic accuracy of EyeGuide focus testing for concussion in elite male rugby players.
Phys Sportsmed
January 2025
World Rugby, Ireland.
Introduction: Smooth pursuit eye movements may be affected by head impacts. The EyeGuide Focus system is a simple, portable, test of visual tracking. This study investigated the diagnostic accuracy of EyeGuide measurements for detection of concussion during elite Rugby matches.
View Article and Find Full Text PDFUnique Pattern of White Matter Hyperintensities in Middle Age and Older Adults with History of Repetitive Head Impact Exposure.
Alzheimers Dement
December 2024
Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA
Background: Repetitive head impacts (RHI) from contact sports can lead to long‐term white matter injury visualized on FLAIR scans as white matter hyperintensities (WMH). The goal of this study was to preliminarily characterize the unique pattern and features of WMH in middle aged‐ to older adults with remote history of exposure to RHI from contact sports.
Method: 76 participants (38 with substantial RHI, 38 with minimal or no RHI) from the Boston University Alzheimer’s Disease Research Center had a FLAIR MRI during their annual study visit.
Is It All in Your Head? Placebo Effects in Concussion Prevention.
Sports Med
January 2025
School of Health Sciences, Swinburne University of Technology, Melbourne, VIC, Australia.
Sports-related concussions (SRCs) are a major health issue in athletes of varying ages, ability levels, and sports. Concerns over the short- and long-term consequences of SRCs have incentivized a wealth of products and policies aimed at reducing SRC risk. Research suggesting the effectiveness of such interventions at reducing SRCs has facilitated their adoption by sports organizations and, in some cases, product commercialization.
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