AI Article Synopsis
- The study aimed to evaluate the effectiveness of the Copenhagen index as a diagnostic tool for ovarian cancer.
- Researchers analyzed data from various medical databases, including a total of 11 studies with 5,266 patients, using statistical software for their calculations.
- Results indicated that the Copenhagen index has high sensitivity (82%) and specificity (88%), suggesting it can accurately diagnose ovarian cancer in clinical settings regardless of a patient's menopausal status.
Article Abstract
Objective: To assess the diagnostic value of the Copenhagen index for ovarian malignancy.
Methods: PubMed, Web of Science, the Cochrane Library, Embase, CBM, CNKI, and WanFang databases were searched throughout June 2021. Statistical analyses were performed using Stata 12, Meta-DiSc, and RevMan 5.3. The pooled sensitivity, specificity, and diagnostic odds ratio were calculated, the summary receiver operating characteristic curve was drawn, and the area under the curve was calculated.
Results: Ten articles, including 11 studies with a total of 5266 patients, were included. The pooled sensitivity, specificity, and diagnostic odds ratio were 0.82 [95% CI (0.80-0.83)], 0.88 [95% CI (0.87-0.89)], and 57.31 [95% CI (32.84-100.02)], respectively. The area under the summary receiver operating characteristics curve and the Q index were 0.9545 and 0.8966, respectively.
Conclusion: Our systematic review shows that the sensitivity and specificity of the Copenhagen index are high enough for it to be used in a clinical setting to provide accurate ovarian cancer diagnosis without considering menopausal status.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266642 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0286650 | PLOS |
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