AI Article Synopsis
- The management of severe neurologic infections from multidrug-resistant (MDR) infections is challenging due to limited treatment options.
- A patient who developed severe meningitis and ventriculitis post-craniotomy was successfully treated with multiple applications of colistin sulfate (intravenous, intrathecal, and aerosol).
- This case suggests that using colistin sulfate in various delivery methods can be an effective last resort for treating hard-to-manage intracranial infections caused by MDR pathogens.
Article Abstract
The management of severe neurologic infections due to multidrug-resistant (MDR) infection remains a challenge. Limited antibiotic treatment regimens make treatment of severe MDR infection more difficult. We describe a patient who developed severe meningitis and ventriculitis after craniotomy caused by MDR and was effectively treated with the administration of multichannel applications (intravenous, intrathecal and aerosol inhalation) of colistin sulfate. This case provides clinical evidence that the intrathecal, intravenous and aerosol inhalation of colistin sulfate by multichannel application can be a last resort in refractory intracranial infection by MDR .
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| http://dx.doi.org/10.2217/fmb-2022-0277 | DOI Listing |
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