Duplication cyst (DC) of the digestive tract is a rare embryological anomaly, presenting as a cystic formation that could be attached to any part of the digestive tract, it is a thin-walled structure made of two layers, an inner layer that is frequently lined by an alimentary epithelium, surrounded by a smooth muscle layer often shared with the adjacent digestive segment. DCs are most commonly located in the distal ileum; sometimes, they are associated with other visceral or skeletal anomalies. They are frequently discovered during childhood, following a bowel obstruction or abdominal pain. Here we report a rare case of an ileal DC lined by a pseudostratified and ciliated epithelium, discovered in an adult patient following intestinal obstruction syndrome.
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http://dx.doi.org/10.7759/cureus.38959 | DOI Listing |
Cell
January 2025
European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton CB10 1SA, UK. Electronic address:
Osteosarcoma is the most common primary cancer of the bone, with a peak incidence in children and young adults. Using multi-region whole-genome sequencing, we find that chromothripsis is an ongoing mutational process, occurring subclonally in 74% of osteosarcomas. Chromothripsis generates highly unstable derivative chromosomes, the ongoing evolution of which drives the acquisition of oncogenic mutations, clonal diversification, and intra-tumor heterogeneity across diverse sarcomas and carcinomas.
View Article and Find Full Text PDFPathol Res Pract
January 2025
Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong 262000, PR China. Electronic address:
Gastric duplication cysts (GDCs) are rare cystic neoplasms that are often difficult to distinguish from other entities. Accurate diagnosis of cysts before resection is difficult even using the most advanced imaging techniques. We present a case of a gastric duplication cyst in a 17-year-old female, presenting with discomfort in the upper abdomen.
View Article and Find Full Text PDFInt Nurs Rev
March 2025
Department of Nursing, Faculty of Health Sciences, Halic University, Istanbul, Turkey.
Aim: To systematically explore the existing literature by examining nursing approaches to home chemotherapy treatment.
Background: With the rising number of patients with cancer, home chemotherapy has gained prominence. Nurses play a crucial role in this process and bear significant responsibilities.
Radiol Case Rep
March 2025
Department of Radiology, National Academy of Medical Sciences (NAMS), Bir Hospital, Mahabouddha, Kathmandu, 44600, Nepal.
Gallbladder duplication is a rare anatomical variation with an incidence of approximately 1 in 3800 to 4000 live births, resulting from aberrant biliary organogenesis. This case report discusses a 35-year-old female who presented with intermittent lower abdominal pain, with initial imaging revealing a complex left adnexal cyst. Follow-up CT and ultrasound examinations revealed 2 distinct gallbladder-like structures in the gallbladder fossa, each with a cystic duct draining into the common bile duct.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
University Surgical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.
Introduction: Duplication of the gallbladder is a rare congenital malformation associated with the development of cholelithiasis. It increases the risk of iatrogenic bile duct injury during cholecystectomy and can lead to symptom recurrence if missed. Although preoperative imaging is helpful, detection rates are around 50 %.
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