has been found as the most abundant pathogenic yeast species under the group Candida-non-albicans. Despite this, it is taxonomically related to and has many of its pathogenic characteristics. Infection with is closely associated with many virulence factors encoded by multiple virulence genes. This study aims to diagnose based on the presence of and to detect many virulence genes. isolates were collected from oral candidiasis patients. Children infected with oral thrush ranging in age from infants to 12 years old provided 150 samples. (66.68 %), (13.21 %), (9.43 %), (7.55 %), and were isolated as types, according to the findings of the present study (2.83%). The presence of the gene was confirmed in the isolates. All isolates were positive for and , while some were positive for (78.5%) and genes (71.4%). Using sequences and phylogenetic trees, it was determined that there was negligible genetic variation between local isolates and global strains. These virulence factor genes play a crucial role in developing infections.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258246 | PMC |
| http://dx.doi.org/10.22092/ARI.2022.359466.2422 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cotton RLP6 Interacts With NDR1/HIN6 to Enhance Verticillium Wilt Resistance via Altering ROS and SA.
Mol Plant Pathol
January 2025
State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources, Hebei Agricultural University, Baoding, China.
Cotton Verticillium wilt (VW) is often a destructive disease that results in significant fibre yield and quality losses in Gossypium hirsutum. Transferring the resistance trait of Gossypium barbadense to G. hirsutum is optional but challenging in traditional breeding due to limited molecular dissections of resistance genes.
View Article and Find Full Text PDFHybrid strains of enterotoxigenic/Shiga toxin-producing , United Kingdom, 2014-2023.
J Med Microbiol
January 2025
NIHR Health Protection Research Unit in Gastrointestinal Infections, University of Liverpool, Liverpool, UK.
Diarrhoeagenic (DEC) pathotypes are defined by genes located on mobile genetic elements, and more than one definitive pathogenicity gene may be present in the same strain. In August 2022, UK Health Security Agency (UKHSA) surveillance systems detected an outbreak of hybrid Shiga toxin-producing /enterotoxigenic (STEC-ETEC) serotype O101:H33 harbouring both Shiga toxin () and heat-stable toxin (). These hybrid strains of DEC are a public health concern, as they are often associated with enhanced pathogenicity.
View Article and Find Full Text PDFModelling host-pathogen interactions: as a platform to study response to host-imposed zinc starvation.
Microbiology (Reading)
January 2025
Department of Biology, Tor Vergata University of Rome, Rome, Italy.
Nutritional immunity, a key component of the vertebrate innate immune response, involves the modulation of zinc availability to limit the growth of pathogens. counteracts host-imposed zinc starvation through metabolic adaptations, including reprogramming of gene expression and activating efficient metal uptake systems. To unravel how zinc shortage contributes to the complexity of bacterial adaptation to the host environment, it is critical to use model systems that mimic fundamental features of -related diseases in humans.
View Article and Find Full Text PDFAutophagy-mediated TET2 degradation by ALV-J Env protein suppresses innate immune activation to promote viral replication.
J Virol
January 2025
College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Unlabelled: Avian leukosis virus subgroup J (ALV-J) poses a significant threat to the poultry industry; yet, our understanding of its replication and pathogenic mechanisms is limited. The Ten-Eleven Translocation 2 (TET2) is an indispensable regulatory factor in active DNA demethylation and immune response regulation. This study reports a significant and time-dependent decrease in TET2 levels following ALV-J infection and shows that the reduction of TET2 protein is mediated by the autophagy pathway.
View Article and Find Full Text PDFEffects of vitamin B supply on cellular processes of the facultative vitamin B consumer .
Appl Environ Microbiol
January 2025
Institute for Chemistry and Biology of the Marine Environment (ICBM), School of Mathematics and Science, Carl von Ossietzky Universität Oldenburg, Oldenburg, Germany.
Vitamin B (cobalamin, herein B) is a key cofactor for most organisms being involved in essential metabolic processes. In microbial communities, B is often scarce, largely because only few prokaryotes can synthesize B and are thus considered B-prototrophs. B-auxotrophy is mostly manifested by the absence of the B-independent methionine synthase, MetE.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!