A Rare Finding of Gastric Pseudomelanosis in Chronic Kidney Disease: A Case Report.

Cureus

Gastroenterology, Borland Groover, Jacksonville, USA.

Published: May 2023

AI Article Synopsis

  • * It’s rarely reported, often noticed in older females with dark stools due to excessive iron use, yet a unique case involved a 75-year-old male with the same issue.
  • * In this case, his blackish stools were attributed to iron tablets for anemia, and an upper endoscopy confirmed the diagnosis of gastric pseudomelanosis.

Article Abstract

Pseudomelanosis is a black-brown discoloration of the loose connective tissue layer of the intestinal mucosa, also known as the lamina propria. Although it is a benign condition and poses no real threat to the patient, it has been known to be associated with certain medication use in the colon, like anthraquinone laxatives, as well as various chronic illnesses in the duodenum and stomach, like iron deficiency anemia, end-stage kidney disease, hypertension, and diabetes mellitus. Only a handful of cases of gastric pseudomelanosis have been reported in the literature, often presenting to the physician as an elderly female with dark, tarry stools from excessive iron use. In this unusual case, a 75-year-old male came to the emergency room due to a concern about blackish stools in the toilet. After reviewing his past medical history, it was found that he takes iron tablets for anemia secondary to end-stage renal disease. While enteric iron was most likely the cause of the melena, an esophagogastroduodenoscopy (EGD) study was performed to rule out any proximal causes of gastrointestinal bleeding. Following the upper endoscopy, gastric pseudomelanosis was established.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257983PMC
http://dx.doi.org/10.7759/cureus.38933DOI Listing

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