Dual Modification of Artificial Protein Cage.

Methods Mol Biol

Department of Bioscience and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Kanagawa, Japan.

Published: June 2023

Chemical modifications of proteins confer new functions on them or modulate their original functions. Although various approaches are developed for modifications, modifications of the two different reactive sites of proteins by different chemicals are still challenging. In this chapter, we show a simple approach for selective modifications of both interior and exterior surfaces of protein nanocages by two different chemicals based on a molecular size filter effect of the surface pores.

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-0716-3222-2_9DOI Listing

Publication Analysis

Top Keywords

dual modification
4
modification artificial
4
artificial protein
4
protein cage
4
cage chemical
4
modifications
4
chemical modifications
4
modifications proteins
4
proteins confer
4
confer functions
4

Similar Publications

L., a medicinal plant renowned for its pharmaceutical alkaloids, has captivated scientific interest due to its rich secondary metabolite profile. This study explores a novel approach to manipulating alkaloid biosynthesis pathways by integrating virus-induced gene silencing (VIGS) with macerozyme enzyme pretreatment.

View Article and Find Full Text PDF

Engineering Lattice Dislocations of TiO Support of PdZn-ZnO Dual-Site Catalysts to Boost CO Hydrogenation to Methanol.

Angew Chem Int Ed Engl

December 2024

Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), State Key Laboratory of Chemical Engineering, Haihe Laboratory of Sustainable Chemical Transformations, Tianjin Key Laboratory of Applied Catalysis Science and Engineering, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072, P. R. China.

CO hydrogenation to methanol using green hydrogen derived from renewable resources provides a promising method for sustainable carbon cycle but suffers from high selectivity towards byproduct CO. Here, we develop an efficient PdZn-ZnO/TiO catalyst by engineering lattice dislocation structures of TiO support. We discover that this modification orders irregularly arranged atoms in TiO to stabilize crystal lattice, and consequently weakens electronic interactions with supported active phases.

View Article and Find Full Text PDF

Carbon Dioxide Upgrading to Biodegradable Plastics through Photo/Electro-Synthetic Biohybrid Systems.

Angew Chem Int Ed Engl

December 2024

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China.

The escalating emissions of anthropogenic carbon dioxide (CO) and the pervasive issue of nondegradable plastic pollution underscore dual urgent challenges in pursuit of a sustainable society. Achieving such sustainability in the plastic industry, while effectively addressing these environmental concerns, necessitates the development and implementation of innovative strategies for the synthesis of biodegradable polymers utilizing CO as feedstocks. The technologies not only facilitate the mitigation of elevated atmospheric CO concentrations but also introduce a renewable carbon resource for polymer manufacturing.

View Article and Find Full Text PDF

Synergistic oxidative modification and covalent cross-linking for the construction of sesbania gum-based high efficiency dust suppression foam sols.

Int J Biol Macromol

January 2025

College of Safety and Environmental Engineering, Shandong University of Science and Technology, Qingdao 266590, China; State Key Laboratory of Mining Disaster Prevention and Control Co-founded by Shandong Province and the Ministry of Science and Technology, Shandong University of Science and Technology, Qingdao 266590, China.

To effectively utilize sesbania gum in coal dust control and address the limitations of excessive viscosity and mediocre strength, oxidation treatment was used to improve its fluidity. Polyvinyl alcohol (PVA) and sodium trimetaphosphite (STMP) were used to enhance oxidized sesbania gum OSG, and crosslinking technology was used to improve its mechanical stability. This study developed a novel foam dust suppressant OSG-PVA/SDBS by response surface design, and the optimized dust suppressant material exhibited excellent adhesion and curing properties.

View Article and Find Full Text PDF

This work describes fully integrated multifolding electrochemical paper-based devices (ePADs) for enhanced multiplexed voltammetric determination of heavy metals (Zn(II), Cd(II), and Pb(II)) using tunable passive preconcentration. The paper devices integrate five circular sample preconcentration layers and a 3-electrode electrochemical cell. The hydrophobic barriers of the devices are drawn by pen-plotting with hydrophobic ink, while the electrodes are deposited by screen-printing.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!