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Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease. | LitMetric

AI Article Synopsis

  • The cerebral lymphatic system is a recently discovered waste removal system in the brain, essential for maintaining central nervous system homeostasis.
  • Understanding its structure and function is crucial for exploring disease pathogenesis and potential therapies.
  • There is a recognized association between the cerebral lymphatic system and diseases affecting the gastrointestinal tract, liver, and kidney, highlighting its role in central-peripheral system interactions.

Article Abstract

As a recently discovered waste removal system in the brain, cerebral lymphatic system is thought to play an important role in regulating the homeostasis of the central nervous system. Currently, more and more attention is being focused on the cerebral lymphatic system. Further understanding of the structural and functional characteristics of cerebral lymphatic system is essential to better understand the pathogenesis of diseases and to explore therapeutic approaches. In this review, we summarize the structural components and functional characteristics of cerebral lymphatic system. More importantly, it is closely associated with peripheral system diseases in the gastrointestinal tract, liver, and kidney. However, there is still a gap in the study of the cerebral lymphatic system. However, we believe that it is a critical mediator of the interactions between the central nervous system and the peripheral system.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10796102PMC
http://dx.doi.org/10.14336/AD.2023.0516DOI Listing

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