Introduction: Hiatus hernia is characterized by axial separation between the lower esophageal sphincter and the crural diaphragm, and higher reflux burden. Impact on reflux is unclear if such separation is intermittent rather than persistent.
Methods: Reflux burden off antisecretory therapy was compared between no hernia (n = 357), intermittent hernia (n = 42), and persistent hernia (n = 155) after review of consecutive high-resolution manometry and reflux monitoring studies.
Results: Proportions with pathologic acid exposure was similar between intermittent and persistent hernia (45.2% vs 46.5%, respectively), and both were significantly different from no hernia (28.7%, P ≤ 0.002).
Discussion: Intermittent hiatus hernias are clinically relevant in gastroesophageal reflux pathophysiology.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.14309/ajg.0000000000002353 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Recurrent Respiratory Distress Caused by Temporary Herniation of Transverse Colon Into Hiatal Hernia in Patient With Kyphosis.
Gastro Hep Adv
October 2024
Department of Gastroenterology, Matsue Seikyo General Hospital, Matsue, Shimane, Japan.
Characterization changes and research waste in randomized controlled trials of global gastroesophageal reflux disease and hiatus hernia over the past 20 years.
Int J Surg
January 2025
Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Background: The results of many large randomized clinical trials (RCTs) have transformed clinical practice in gastroesophageal reflux disease (GERD) and esophageal hiatal hernia (HH). However, research waste (i.e.
View Article and Find Full Text PDFEffectiveness of Abdominal Breathing Exercise to Control Gastroesophageal Reflux Disease, a Randomized Controlled Trial.
J Community Hosp Intern Med Perspect
January 2025
Holy Family Hospital, Rawalpindi, Pakistan.
Objectives: To determine the effect of actively training the crura of diaphragm which is a part of lower esophageal sphincter using abdominal breathing exercises to treat gastroesophageal reflux disease.
Methodology: With a randomized controlled study design, a total of 22 (11 in each group) clinically diagnosed patients of GERD presenting to the gastroenterology outpatient department at Holy Family Hospital in Pakistan were assessed using GERD related "quality of life index (QoLI)" questionnaire and their on-demand proton pump inhibitors (PPI) usage. Single blinding technique will be used.
Hiatal Hernia in an Elderly Patient Complicated by Upper Gastroesophageal Bleeding, Pulmonary Embolism, and Respiratory Failure: A Case Report.
Cureus
December 2024
Internal Medicine, Salmaniya Medical Complex, Manama, BHR.
Hiatal hernias occur when abdominal contents protrude into the posterior mediastinum through the esophageal hiatus of the diaphragm. They are classified into four types, with Type I (sliding) being the most prevalent. We report a case of a patient diagnosed with a large Type IV paraesophageal hernia.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!