The linear lipopeptides okeaniamide A () and okeaniamide B () were isolated from an sp. marine cyanobacterium collected in Okinawa. The structures of these compounds were established by spectroscopic analyses, and the absolute configurations were elucidated based on a combination of chemical degradations, Marfey's analysis, and derivatization reactions. Okeaniamide A () and okeaniamide B () dose-dependently promoted the differentiation of mouse 3T3-L1 preadipocytes in the presence of insulin.
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