Activatable BODIPY-chromene NIR-II probes with small spectral crosstalk enable high-contrast bioimaging.

Chem Commun (Camb)

Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science & Technology, Shanghai 200237, China.

Published: July 2023

Herein, we design a novel "crossbreeding" dye (BC-OH) within the second near-infrared (NIR-II) window based on BODIPY and chromene chromophores. BC-OH can serve as a platform to construct activatable NIR-II probes with small spectral crosstalk, thereby making a breakthrough in imaging HO fluctuation in an APAP-induced liver injury model with high signal-to-background ratio.

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Source
http://dx.doi.org/10.1039/d3cc01742gDOI Listing

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