A Rare Cause of Abdominal Pain: Erdheim-Chester Disease.

ACG Case Rep J

Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

Published: June 2023

A 65-year-old man presented with hematuria, night sweats, nausea, intermittent nonbloody diarrhea, and abdominal pain. Computed tomography angiogram with enterography showed retroperitoneal fibrosis surrounding both kidneys and ureters without any evidence of vascular obstruction or hydronephrosis. Laparoscopic biopsy demonstrated fibroadipose tissue involved by a subtle histiocytic infiltrate in a background of marked fibrosis, scattered lymphocytes, and plasma cells. The histiocytes strongly expressed CD163, Factor XIIIa, and . He was diagnosed with Erdheim-Chester disease, a rare histiocytic neoplasm uncommonly presenting with gastroenterological manifestations.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249710PMC
http://dx.doi.org/10.14309/crj.0000000000001049DOI Listing

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