AI Article Synopsis
- Fasciolosis is a parasitic disease that affects the liver and bile ducts in livestock, making control measures crucial in areas where it is common.
- This study examines the impact of ethanolic extracts on different life stages of the parasite, showing that varying concentrations significantly reduced the development of eggs and killed adult flukes within certain time frames.
- The findings suggest that the extract possesses effective anthelmintic properties against the parasite F. gigantica, evidenced by observed damage to the parasites' structures.
Article Abstract
Background: Fasciolosis is a parasitic disease affecting the hepatobiliary system of livestock worldwide. The control of the fluke is important to be performed in endemic regions.
Aim: This study aims to evaluate the effect of ethanolic extract on egg and adult stadia of .
Methods: in different stages were incubated with ethanolic extract in different concentrations and time points.
Results: The number of developed eggs with different concentrations of 1.25%, 2.5%, and 5% was significantly decreased by 36.67%, 56.67%, and 56.67% on day 11 post-incubation, which showed an ovicidal effect of the herb. The developed eggs on day 14, which were represented by hatched larvae, were also decreased by 70%, 50%, and 13.33%, respectively. Significant flukicidal effects were observed in the incubation time of 80 minutes for the concentration of 20% ( = 0.007) and 640 minutes for 10% concentration ( = 0.003). Surface microscopy of adult showed damaged skin and spina with the erosion of the inner membrane and detached syncytium from the tegument.
Conclusion: Overall, the results indicate that has a promising anthelmintic property against F. gigantica in both ova and adult stages.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257460 | PMC |
| http://dx.doi.org/10.5455/OVJ.2023.v13.i5.10 | DOI Listing |
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