Background: These days minimally invasive micro-osteoperforation (MOPs) has accelerated orthodontic tooth movement (OTM). However, there are some conflicting reports about their various impacts; hence, the present systematic review study aimed to evaluate the effect of MOP on root resorption, pulp vitality, and the biological changes of teeth subjected to OTM.
Materials And Methods: Search in electronic databases of English literature including PubMed, Scopus, Web of sciences, Cochrane, and Google scholar as well as a manual search was performed from 2013 to 2022. Most of the studies included in this article were randomized controlled trials.
Results: From the total number of 321 found articles, 31 duplicated and 268 irrelevant articles were excluded regarding the defined inclusion and exclusion criteria. Consequently, 22 articles were subjected to the quality assessment process, and finally, 18 articles were selected for the review phase. Root resorption during tooth movement using the MOP approach was reported only in one study. Besides, except for two animal studies, all of the relevant included articles showed that MOPs significantly increased the expression of some inflammatory biomarkers known to recruit osteoclast precursors and increase the number of osteoclast cells. On the other hand, two animal studies showed no differences in osteoclast counts by using MOPs in comparison to their control groups, which was consequently the result of biologic variability between animal and human and also probably the small sample sizes of these two studies.
Conclusion: In this systematic review, according to the adverse effects of MOP on root resorption, one study showed higher levels of root resorption among patients undergoing MOP. However, this outcome was due to the different methods used to evaluate the effect of MOPs on root resorption. Moreover, a high certainty of evidence supports that MOP causes biological changes and an elevation in cytokines, chemokines, and other biomarkers that stimulates osteoclasts differentiation which in turn accelerate OTM. There was no change in pulp vitality status based on available evidence.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247875 | PMC |
Publication Analysis
Top Keywords
Similar Publications
Clear cell variant of calcifying epithelial odontogenic tumour (Pindborg tumour) of the mandible.
BMJ Case Rep
January 2025
Department of Oral and Maxillofacial Surgery, Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth (Deemed to be University), Pondicherry, India.
A calcifying epithelial odontogenic tumour (CEOT) is a rare benign odontogenic tumour of epithelial origin accounting for approximately 1% of all odontogenic tumours. The intraosseous form occurs more commonly in the posterior mandible whereas the extraosseous form is common in the anterior maxilla. CEOT is often asymptomatic and presents with a painless swelling of the mandible.
View Article and Find Full Text PDFObturation of Simulated Internal Resorption Cavities With Four Different Techniques and a Hydraulic Root Canal Sealer: A Comparative Stereomicroscopic Evaluation.
Cureus
December 2024
Conservative Dentistry and Endodontics, Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Aim To compare the quality of obturation using WVC (warm vertical compaction), CLC (cold lateral compaction), injectable (iFill), and Thermafil (GuttaCore) techniques, along with hydraulic condensation of bioceramic (BC) sealer, and evaluating the percentage of gutta-percha (GP), sealer, and voids in simulated internal resorptive lesions, using an advanced stereomicroscope with ImageJ software (National Institutes of Health, Bethesda, MD, USA). Methods and material In this study, 40 freshly extracted maxillary incisors were collected, and endodontic instrumentation was done to working length using hand K-files. Simulated internal resorption cavities were created in the middle-apical third of the roots after horizontal sectioning and were re-cemented.
View Article and Find Full Text PDFA Case of Hypophosphatasia Started Enzyme Replacement Therapy Since Babyhood Stage.
Children (Basel)
January 2025
Department of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
Background: Hypophosphatasia (HPP) is an inherited disease caused by low activity of tissue-nonspecific alkaline phosphatase. Dental characteristics include premature loss of primary teeth, enlarged pulp chambers, and enamel hypoplasia. Although enzyme replacement therapy with asfotase alfa was approved in 2015, there are few reports about the dental outcomes of this treatment.
View Article and Find Full Text PDFEffect of customized 3D-printed MARPE appliance on hard tissues, soft tissues, and airway: A prospective CBCT study.
J World Fed Orthod
January 2025
Department of Orthodontics and Dentofacial Orthopaedics, Manav Rachna Dental College, Manav Rachna International Institute of Research and Studies, Faridabad, Haryana, India.
Background: The advances in technology have enabled the customization of appliances including mini-screw-assisted rapid palatal expansion (MARPE) appliances for skeletal expansion in young adult patients. The study assessed the short-term effects of customized MARPE appliances on the hard tissues, soft tissues, and airway volume over a period of 6 months.
Methods: A total of 15 patients in the age range of 15 to 25 years were treated for transverse maxillary deficiency using a three-dimensional (3D) printed customized MARPE appliance.
Biomechanical and Biological Multidisciplinary Strategies in the Orthodontic Treatment of Patients with Periodontal Diseases: A Review of the Literature.
Bioengineering (Basel)
January 2025
Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, 95124 Catania, Italy.
Orthodontic treatment aims to correct malocclusions and ensure the overall health and stability of the periodontium. The relationship between orthodontic therapy and periodontal health is intricate and multifaceted, and a comprehensive approach is often required to achieve optimal outcomes. Firstly, this article delves into the impact of orthodontic mechanics on periodontal tissues, emphasizing the importance of minimizing iatrogenic effects such as root resorption and gingival recession.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!