AI Article Synopsis

  • Long COVID affects both adults and children, but there's a lack of understanding regarding its clinical and diagnostic aspects, especially in younger populations.
  • Two sisters, previously high achievers, experienced severe neurocognitive issues after their COVID-19 infection, which were initially mistaken for psychological distress.
  • Their case reveals significant brain hypometabolism, suggesting that lasting symptoms in children post-infection may stem from organic causes, underscoring the need for better diagnostic and treatment options.

Article Abstract

Background: Long coronavirus disease (COVID) is increasingly recognized in adults and children; however, it is still poorly characterized from a clinical and diagnostic perspective, particularly in the younger populations.

Case Presentation: We described the story of two sisters-with high social and academic performance before their severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-who reported severe neurocognitive problems, initially classified as psychologic pandemic distress and eventually found to have significant brain hypometabolism.

Conclusions: We provided a detailed clinical presentation of neurocognitive symptoms in two sisters with long COVID associated with brain hypometabolism documented in both sisters. We believe that the evidence of objective findings in these children further supports the hypothesis that organic events cause persisting symptoms in a cohort of children after SARS-CoV-2 infection. Such findings highlight the importance of discovering diagnostics and therapeutics.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251436PMC
http://dx.doi.org/10.3389/fped.2023.1165072DOI Listing

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