Risk factors in childhood diabetes mellitus.

Acta Paediatr Hung

Published: September 1986

AI Article Synopsis

  • The study analyzed the ratios of total cholesterol/HDL-cholesterol and free fatty acid/albumin in different groups of diabetic patients, noting changes due to physical activity.
  • Patients with poor diabetes control showed increased levels of both cholesterol ratios, whereas low albumin levels were linked to very poor control or complications.
  • Increased physical activity consistently reduced the total cholesterol/HDL-cholesterol ratio, while children with good control but low physical activity had an opposite trend, indicating that both ratios are valuable indicators of diabetes management.

Article Abstract

The quotients total cholesterol/HDL-cholesterol and free fatty acid/albumin in serum were examined in various groups of diabetic patients and the changes of the quotients induced by various forms of physical activity were then registered. Both total cholesterol/HDL-cholesterol and free fatty acid/albumin were increased in patients with unsatisfactory control of diabetes. Low albumin levels were only seen in cases with very poor control or in cases afflicted by complications. Increased muscular activity unvariably led to a fall in the value of total cholesterol/HDL-cholesterol while in children with adequate control but performing little physical exercise the quotient of free fatty acid/albumin was low and total cholesterol/HDL-cholesterol was increased. In addition to the quotient of total cholesterol/HDL-cholesterol also the quotient of free fatty acid/albumin is a sensitive indicator of the diabetic condition.

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