Factors Associated with Intestinal Polyp Recurrence after Electroresection.

Objective: To investigate the frequency of recurrence after colonoscopic high-frequency electroresection of intestinal polyps and analyse the risk factors associated with recurrence.

Study Design: Observational study. Place and Duration of the Study: Second People's Hospital of Hefei, China, from January 2017 to January 2021.

Methodology: Clinical data of 240 patients with intestinal polyps who underwent high-frequency electroresection were analysed. After two years, patients with recurring polyps were categorised into recurrence or non-recurrence groups. Intestinal polyp recurrence was the dependent variable, and patient characteristics, medical history, and gastrointestinal parameters were independent variables. Variables significant in univariate analysis were included in unconditional binary logistic regression analysis.

Results: No significant difference was found in gender, BMI, smoking history, drinking history, previous gastrointestinal bleeding, location of polyps, intestinal cleanliness, and high-fat diet between groups (p >0.05). Age (≥60 years), number of polyps (≥3), diameter (≥2 cm), adenomatous polyps, Helicobacter pylori infection, metabolic syndrome proportion, and C-reactive protein levels were significantly higher in the recurrent group (p <0.05). Multivariate analysis revealed age (≥60 years), number of polyps (≥3), diameter (≥2 cm), adenomatous polyps, and metabolic syndrome as the factors associated with recurrence (p<0.05).

Conclusion: Age, greater number of intestinal polyps, larger diameter, histopathological type, and the presence of metabolic syndrome are factors influencing intestinal polyp recurrence after endoscopic high-frequency electroresection.

Key Words: Intestinal polyps, Colonoscope, High-frequency electroresection, Recurrence.