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Impact of intrarenal arterial lesions on prognosis of IgA nephropathy: insights from a retrospective cohort study.
Ren Fail
December 2025
Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
Background: IgA nephropathy (IgAN) presents a challenging spectrum of outcomes, often complicated by intrarenal arterial/arteriolar lesions (IALs) in affected individuals. Despite their clinical relevance, existing criteria for classifying and assessing the severity of these lesions remain undefined. This study aimed to establish semi-quantitative assessment criteria for grading IALs and to evaluate their prognostic significance in patients with IgAN.
View Article and Find Full Text PDFEvaluation of Long-term Outcomes and its Related Factors in Patients with Immune-complex Mediated Glomerulonephritis: A 20-Year Historical Cohort Study in Iran.
Iran J Kidney Dis
February 2025
Department of Medicine, Nephrology Section, Hasheminejad Kidney Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Introduction: Immune-complex mediated glomerulonephritis (IC-GN) has a poor prognosis and commonly leads to kidney failure This study reports 20-year experience with the long-term outcomes of 222 Iranian IC-GN patients.
Methods: This single-center historical cohort study was conducted on patients who underwent kidney biopsies from 1998 to 2018 in Hasheminejad Kidney Center (HKC). Initial demographic, clinical, laboratory, and pathology data were extracted from the glomerulonephritis registry of HKC.
Rare presentation of recurrent eosinophilic cystitis in a child.
BMJ Case Rep
March 2025
Paediatric Surgery, John Radcliffe Hospital, Oxford, UK
Eosinophilic cystitis (EC) is a rare presentation in childhood, with just over 100 cases reported in the literature. It often presents with haematuria and irritative lower urinary tract symptoms (LUTS) including frequency, urgency and dysuria. EC can be treated conservatively or surgically.
View Article and Find Full Text PDFBucillamine-induced membranous nephropathy versus primary membranous nephropathy: comparing pathological features and kidney prognosis.
Sci Rep
March 2025
Department of Pathology, Toranomon Hospital, Tokyo, Japan.
To evaluate the pathological and clinical course differences between bucillamine‑induced membranous nephropathy (BCL-MN) and primary membranous nephropathy (p-MN). This retrospective cohort study included 29 BCL-MN patients and 98 p-MN patients at two hospitals from 2000 to 2019. We compared the kidney biopsy findings and clinical course between the BCL-MN and p-MN groups, focusing on pathological differences, proteinuria relapse rates, and 30% or greater decrease in the eGFR.
View Article and Find Full Text PDFThe utilization of c-type natriuretic peptide levels on experimental muscle and kidney ischemia/reperfusion model.
Malawi Med J
October 2024
Varis Clinic, Department of Cardiovascular Surgery, Ankara, Türkiye.
Introduction: C-type Natriuretic Peptide (CNP) is the third natriuretic peptide (NP) identified from the nervous system and endothelial cells. CNP is believed to be produced locally in tubular cells and glomeruli of kidneys. We aim to determine the clinical value of CNP levels at lower extremity muscle ischemia/reperfusion (I/R), kidney I/R, and both I/R models and evaluate them in laboratory practices.
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