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The impact of an interactive online informational and peer support application (app) for patients with low anterior resection syndrome (LARS) on quality of life: a multicenter randomized controlled trial.
Surg Endosc
January 2025
McGill University, Cleveland Clinic Florida, 2950 Cleveland Clinic Blvd., Weston, FL, 33301, USA.
Introduction: Low Anterior Resection Syndrome (LARS) describes bowel dysfunction post-restorative proctectomy (RP) and is associated with poor quality of life (QoL). The aim of this study was to assess the impact of an interactive online informational and peer support App on participants' QoL (primary outcome), LARS, and emotional distress (secondary outcomes).
Methods: A multicentre, randomized, parallel-group trial was conducted across five Canadian colorectal surgery practices.
Disability-Adjusted Life Years (DALYs) due to Breast, Cervical, Colorectal and Oral Cancers in Taiwan Regions.
Cancer Med
January 2025
Department of Bioenvironmental Systems Engineering, National Taiwan University, Taipei, Taiwan.
Background: Cancer is a leading cause of death globally, with significant variations in incidence and mortality rates among different cancer types and regions. In Taiwan, breast cancer (BC), cervical cancer (CxCa), colorectal cancer (CRC), and oral cancer (OC) are prevalent and have prompted government-led screening programs to mitigate their impact. This study aims to assess the burden of these cancers at the county scale using disability-adjusted life years (DALYs) as a metric, focusing on the years 2010, 2015, 2018, 2019, and 2020.
View Article and Find Full Text PDFA Novel Lineage of Endosymbiotic Actinomycetales: Genome Reduction and Acquisition of New Functions in Bifidobacteriaceae Associated With Termite Gut Flagellates.
Environ Microbiol
January 2025
Research Group Insect Gut Microbiology and Symbiosis, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Cellulolytic flagellates are essential for the symbiotic digestion of lignocellulose in the gut of lower termites. Most species are associated with host-specific consortia of bacterial symbionts from various phyla. 16S rRNA-based diversity studies and taxon-specific fluorescence in situ hybridization revealed a termite-specific clade of Actinomycetales that colonise the cytoplasm of Trichonympha spp.
View Article and Find Full Text PDFGlobal, regional, and national survey on burden and Quality of Care Index (QCI) of orofacial clefts: Global burden of disease systematic analysis 1990-2019.
PLoS One
January 2025
Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Background: Orofacial clefts are the most common craniofacial anomalies that include a variety of conditions affecting the lips and oral cavity. They remain a significant global public health challenge. Despite this, the quality of care for orofacial clefts has not been investigated at global and country levels.
View Article and Find Full Text PDFExploring oral health challenges and integration strategies in opioid treatment programs: perspectives from clinicians and clients.
Aust J Prim Health
January 2025
Drug and Alcohol Services, Northern Sydney Local Health District, NSW Health, St Leonards, NSW, Australia; and Specialty of Addiction Medicine, Northern Clinical School, The University of Sydney, St Leonards, NSW, Australia; and National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia.
Background Despite the paramount importance of oral health, individuals undergoing treatment for opioid use disorder face unique challenges beyond traditional addiction care. This qualitative study explores the challenges Opioid Treatment Program (OTP) clients in Australia encounter when accessing oral health care, aiming to understand the underlying factors and identify effective strategies for integrating oral health into an OTP. Methods Semi-structured interviews were conducted with OTP clients, OTP clinicians and oral health clinicians using tested interview guides.
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