Much guidance on statistical training in STEM fields has been focused largely on the undergraduate cohort, with graduate education often being absent from the equation. Training in quantitative methods and reasoning is critical for graduate students in biomedical and science programs to foster reproducible and responsible research practices. We argue that graduate student education should more center around fundamental reasoning and integration skills rather than mainly on listing 1 statistical test method after the other without conveying the bigger context picture or critical argumentation skills that will enable student to improve research integrity through rigorous practice. Herein, we describe the approach we take in a quantitative reasoning course in the R3 program at the Johns Hopkins Bloomberg School of Public Health, with an error-focused lens, based on visualization and communication competencies. Specifically, we take this perspective stemming from the discussed causes of irreproducibility and apply it specifically to the many aspects of good statistical practice in science, ranging from experimental design to data collection and analysis, and conclusions drawn from the data. We also provide tips and guidelines for the implementation and adaptation of our course material to various graduate biomedical and STEM science programs.
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http://dx.doi.org/10.1371/journal.pcbi.1011160 | DOI Listing |
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December 2024
College of Economics and Management, Huazhong Agricultural University, Wuhan, 430070, Hubei, China.
In light of the Chinese government's dual carbon goals, achieving cleaner production activities has become a central focus, with regional environmental collaborative governance, including the management of agricultural carbon reduction, emerging as a mainstream approach. This study examines 268 prefecture-level cities in China, measuring the carbon emission efficiency of city agriculture from 2001 to 2022. By integrating social network analysis and a modified gravity model, the study reveals the characteristics of the spatial association network of city agricultural carbon emission efficiency in China.
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December 2024
Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA, 92697, USA.
Preserving the ability to vividly recall emotionally rich experiences contributes to quality of life in older adulthood. While prior works suggest that moderate-intensity physical activity (MPA) may bolster memory, it is unclear whether this extends to emotionally salient memories consolidated during sleep. In the current study, older adults (mean age = 72.
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December 2024
Department of Orthopedics, The Second Affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi Province, China.
The DNA cross-link repair 1B (DCLRE1B) gene is involved in repairing cross-links between DNA strands, including those associated with Hoyeraal-Hreidarsson syndrome and congenital dyskeratosis. However, its role in tumours is not well understood. DCLRE1B expression profiles were examined in tumour tissues and normal tissues using TCGA, GTEx, and TARGET datasets.
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December 2024
Department of Orthopaedics and Traumatology, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Establishing normative values and understanding how proprioception varies among body parts is crucial. However, the variability across individuals, especially adolescents, makes it difficult to establish norms. This prevents further investigation into classifying patients with abnormal proprioception.
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December 2024
School of Civil Engineering and Architecture, Wuhan University of Technology, Wuhan, 430070, China.
Urban rail transit systems, represented by subways, have significantly alleviated the traffic pressure brought by urbanization and have addressed issues such as traffic congestion. However, as a commonly used construction method for subway tunnels, shield tunneling inevitably disturbs the surrounding soil, leading to uneven ground surface settlement, which can impact the safety of nearby buildings. Therefore, it is crucial to promptly obtain and predict the ground surface settlement induced by shield tunneling construction to enable safety warnings and evaluations.
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