Deformable image registration is a process to determine the non-linear spatial correspondence among deformed image pairs. Generative registration network is a novel structure involving a generative registration network and a discriminative network that encourages the former to generate better results. We propose an Attention Residual UNet (AR-UNet) to estimate the complicated deformation field. The model is trained using perceptual cyclic constraints. As an unsupervised method, we require labelling for training and use virtual data augmentation to improve the robustness of the proposed model. We also introduce comprehensive metrics for image registration comparison. Experimental results show quantitative evidence that the method can predict reliable deformation field at a reasonable speed and outperform conventional learning based and non-learning based deformable image registration methods.
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http://dx.doi.org/10.1109/TCBB.2023.3284215 | DOI Listing |
J Pain Res
January 2025
Department of Acupuncture-Moxibustion and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People's Republic of China.
Purpose: Knee osteoarthritis (KOA) is a prevalent degenerative bone and joint disease observed in clinical practice. While acupuncture has demonstrated efficacy in treating KOA, the central mechanisms underlying its effects remain ambiguous. Recently, functional magnetic resonance imaging (fMRI) has been extensively applied in studying the brain mechanisms of acupuncture analgesia.
View Article and Find Full Text PDFCancer Imaging
January 2025
Department of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Hongkou District, No. 100, Haining Road, Shanghai, 200080, China.
Background: Programmed cell death 1/programmed death ligand-1 (PD-L1)-based immune checkpoint blockade is an effective treatment approach for non-small-cell lung cancer (NSCLC). However, immunohistochemistry does not accurately or dynamically reflect PD-L1 expression owing to its spatiotemporal heterogeneity. Herein, we assessed the feasibility of using a Ga-labeled anti-PD-L1 nanobody, Ga-NODAGA-NM-01, for PET imaging of PD-L1.
View Article and Find Full Text PDFBiomed Eng Online
January 2025
Department of Pulmonary and Critical Care Medicine, National Health Commission Key Laboratory of Pneumoconiosis, Shanxi Key Laboratory of Respiratory Diseases, First Hospital of Shanxi Medical University, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, People's Republic of China.
Background: Coal workers' pneumoconiosis is a chronic occupational lung disease with considerable pulmonary complications, including irreversible lung diseases that are too complex to accurately identify via chest X-rays. The classification of clinical imaging features from high-resolution computed tomography might become a powerful clinical tool for diagnosing pneumoconiosis in the future.
Methods: All chest high-resolution computed tomography (HRCT) medical images presented in this work were obtained from 217 coal workers' pneumoconiosis (CWP) patients and dust-exposed workers.
BMC Anesthesiol
January 2025
Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkla, 90110, Thailand.
Background: A previous study showed that airway ultrasound, specifically the distance from the skin to the hyoid bone (DSHB), may be correlated with a higher risk of difficult mask ventilation (DMV). However, the study was conducted in Italy and lacks data for the Asian and Thai populations. This study aimed to predict DMV using pre-operative ultrasonography to measure the DSHB and from the skin to the thyroid isthmus (DSTI) in Thai patients undergoing elective surgery under general anesthesia.
View Article and Find Full Text PDFNPJ Digit Med
January 2025
Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Chatbot-based multimodal AI holds promise for collecting medical histories and diagnosing ophthalmic diseases using textual and imaging data. This study developed and evaluated the ChatGPT-powered Intelligent Ophthalmic Multimodal Interactive Diagnostic System (IOMIDS) to enable patient self-diagnosis and self-triage. IOMIDS included a text model and three multimodal models (text + slit-lamp, text + smartphone, text + slit-lamp + smartphone).
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