AI Article Synopsis
- Allogeneic tissue products are prevalent in clinical treatments because they have a wider sourcing and cause less trauma to patients compared to using their own (autologous) tissues.
- However, harmful substances can leach from the organic solvents used in these products into patients during treatment, posing health risks.
- The study focuses on identifying and analyzing these leachable substances, establishing detection methods to ensure patient safety in the use of allogeneic products.
Article Abstract
Products made from allogeneic tissue are largely used in clinical treatment due to its wide source compared with autologous tissue, causing less secondary trauma of patients and the good biocompatibility. Various organic solvents and other substances introduced in the production process of allogeneic products will leach down into the human through clinical treatment, thus bringing varying degrees of harm to patients. Therefore, it is very necessary to detect and control the leachables in such products. Based on the classification and summary of leachable substances existing in the allogeneic products, the preparation of extract and the establishment of the detection techniques for known and unknown leachable are briefly introduced in this study, in order to provide research method for the study of leachable substances of allogeneic products.
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| http://dx.doi.org/10.3969/j.issn.1671-7104.2023.03.021 | DOI Listing |
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