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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243603 | PMC |
| http://dx.doi.org/10.54111/0001/iii1 | DOI Listing |
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Pushing the Boundaries of Living Donation Through Kidney Paired Donation.
Am J Kidney Dis
December 2024
Division of Nephrology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA. Electronic address:
Living donor kidney transplant (LDKT) is the treatment of choice for patients with advanced kidney disease. Kidney paired donation (KPD), originally proposed to overcome immunological barriers, has now evolved to address biological and chronological incompatibilities and reduce financial disincentives. This strategy has allowed maximization of the number of LDKTs.
View Article and Find Full Text PDFModel-informed drug discovery and development approaches to inform clinical trial design and regulatory decisions: A primer for the MENA region.
Saudi Pharm J
December 2024
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Model-Informed Drug Discovery and Development (MID3) represents a transformative approach in pharmaceutical research, integrating quantitative models to inform and optimize decision-making throughout the drug development process. This review explores the current applications, challenges, and future prospects of MID3 within the Middle East and North Africa (MENA) region. By leveraging local data and advanced computational techniques, MID3 has the potential to significantly enhance the efficiency and success rates of drug development tailored to regional health priorities.
View Article and Find Full Text PDFRegional Water and Food Security Require Joint Israeli-Palestinian Guidelines for Wastewater Reuse and Food Safety.
Food Nutr Bull
December 2024
Faculty of Social Sciences, Tel Aviv University, Tel Aviv, Israel.
Background: Water and food security in Israel and the Palestinian Authority are deeply interconnected due to the region's arid climate and water scarcity, shared water resources, and interrelated agricultural sectors. Therefore, jointly addressing water reuse is vital to supporting sustainable agricultural production and ensuring food safety.
Objectives: This paper examines the food safety implications of the cross-border trade of fresh fruits and vegetables between the Palestinian Authority and Israel, with an emphasis on the influence of, water technologies, agricultural practices, and environmental health.
Youth Sports Betting and Problem Gambling in the Global and Nigerian Context: A Review.
Niger Med J
November 2024
Community and Clinical Research Division, First On-Call Initiative, Port Harcourt, Nigeria.
Article Synopsis
- Sports betting has shifted significantly from physical venues to online platforms, attracting a large number of young adults, particularly in the Americas, Europe, and Nigeria, highlighting diverse sports interests across regions.
- The review highlights the risks associated with sports betting, including financial losses and psychosocial issues like academic decline and mental health problems, stressing the urgent need for regulated measures to mitigate potential harms.
- Socio-demographic factors influence participation in betting, with motivations ranging from monetary gain to social interaction, necessitating a collaborative approach by betting companies and regulators to promote responsible gambling and public awareness.
Antibiotic Dispensing Practices Among Community Retail Pharmacies and Registered Drugstores: Results from a Simulated Client Study in Lilongwe, Malawi.
Integr Pharm Res Pract
November 2024
Clinical Research Education and Management Services (CREAMS), Lilongwe, Malawi.
Introduction: Antimicrobial resistance (AMR) is largely driven by the inappropriate use of antibiotics. This has been attributed to the non-prescription sale of antibiotics in retail drug outlets. Despite the rising number of retail drug outlets in Malawi, the practice of drug dispensing in private pharmacies has not been evaluated.
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