Chronic pain is no more prevalent in people living with HIV than in their uninfected counterparts in South Africa.

Eur J Pain

Brain Function Research Group, Faculty of Health Sciences, School of Physiology, University of the Witwatersrand, Johannesburg, South Africa.

Published: November 2023

AI Article Synopsis

  • The study aimed to estimate and compare chronic pain prevalence between individuals living with HIV (HIV+) and those without HIV (HIV-), as previous research on this topic was limited.
  • Data was collected from a large sample of 6,584 participants aged 15 and older in the 2016 South African Demographic and Health Survey, revealing that approximately 20% of both HIV+ and HIV- groups reported chronic pain.
  • The findings suggest that living with HIV does not significantly increase the risk of chronic pain, challenging the common belief that HIV+ individuals experience higher levels of chronic pain compared to HIV- individuals.

Article Abstract

Background: There are few studies on chronic pain prevalence in people living with HIV, and there are no studies comparing chronic pain prevalence in an HIV-infected group (HIV+) to that found in an uninfected group (HIV-) in the same population. This study was undertaken to (1) estimate the chronic pain prevalence in HIV+ individuals and (2) compare chronic pain prevalence between HIV+ and HIV- groups in a population.

Methods: Individuals ≥15 years old were recruited using multi-stage probability sampling in the 2016 South African Demographic and Health Survey. In an interview, participants were asked whether they currently had pain or discomfort, and if so, whether that pain or discomfort had persisted for at least 3 months (operational definition of chronic pain). Blood samples were taken from a volunteering sub-sample for HIV testing.

Results: A total of 6584 of 12,717 eligible individuals answered the questionnaire and were tested for HIV. Mean age: 39.1 years (95% confidence interval [CI]: 38.3-39.9), per cent female: 55% (95% CI: 52-56) and tested HIV+: 19% (95% CI: 17-20). The prevalence of chronic pain was 19% (95% CI: 16-23) in the HIV+ group, which was similar to that found in the HIV- group (20% [95% CI: 18-22]; odds ratio [adjusted for age, sex, socio-economic status] = 0.93 [95% CI: 0.74-1.17], p-value = 0.549).

Conclusion: The prevalence of chronic pain in South Africans living with HIV was approximately 20%, and having HIV was not associated with an increased risk of chronic pain.

Significance: Using data from a large, national, population-based study in South Africa, I show for the first time that the prevalence of chronic pain in that population did not differ materially between the part of the population that was living with HIV compared with their uninfected counterparts (both approximately 20%). These findings run counter to the dogma that there is a greater risk of having pain in people living with HIV.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10947087PMC
http://dx.doi.org/10.1002/ejp.2144DOI Listing

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