[Lignans from stems and leaves of Cephalotaxus fortunei (Ⅱ)].

Zhongguo Zhong Yao Za Zhi

Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, School of Chinese Materia Medica, Shenyang Pharmaceutical University Shenyang 117004, China.

Published: April 2023

The present study aimed to explore the chemical constituents from the stems and leaves of Cephalotaxus fortunei. Seven lignans were isolated from the 75% ethanol extract of C. fortunei by various chromatographic methods, including silica gel, ODS column chromatography, and HPLC. The structures of the isolated compounds were elucidated according to physicochemical properties and spectral data. Compound 1 is a new lignan named cephalignan A. The known compounds were identified as 8-hydroxy-conidendrine(2), isolariciresinol(3), leptolepisol D(4), diarctigenin(5), dihydrodehydrodiconiferyl alcohol 9'-O-β-D-glucopyranoside(6), and dihydrodehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside(7). Compounds 2 and 5 were isolated from the Cephalotaxus plant for the first time.

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Source
http://dx.doi.org/10.19540/j.cnki.cjcmm.20220928.201DOI Listing

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