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[Structure-activity relationship of Lycium barbarum polysaccharides]. | LitMetric

[Structure-activity relationship of Lycium barbarum polysaccharides].

Zhongguo Zhong Yao Za Zhi

Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Key Laboratory of Chinese Medicinal Resources Recycling Utilization of State Administration of Traditional Chinese Medicine Nanjing 210023, China.

Published: May 2023

AI Article Synopsis

  • The fruits of Lycium barbarum, a traditional Chinese herb, have been used for thousands of years and contain active components called Lycium barbarum polysaccharides (LBPs) that offer various health benefits.
  • LBPs have notable properties including immunomodulatory effects, antioxidant capacity, and potential anti-tumor and neuroprotective activities, which are influenced by factors like molecular weight and structure.
  • The research reviews the current understanding of LBPs’ structure and functions, identifies challenges in studying their health benefits, and aims to guide future research and practical applications.

Article Abstract

As a traditional Chinese herb and functional food, the fruits of Lycium barbarum has been widely used for thousands of years in China. L. barbarum polysaccharides(LBPs) are predominant active components, which have immunomodulatory, antioxidant, hypoglycemic, neuroprotective, anti-tumor, and prebiotic activities. The molecular weight, monosaccharide composition, glycosidic bond, branching degree, protein content, chemical modification, and spatial structure of LBPs are closely related to their biological activity. Based on the previous studies of this research team, this paper systematically combed and integrated the research progress of structure, function, and structure-activity relationship of LBPs. At the same time, some problems restricting the clarification of the structure-activity relationship of LBPs were considered and prospected, hoping to provide references for the high value utilization of LBPs and in-depth exploration of their health value.

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Source
http://dx.doi.org/10.19540/j.cnki.cjcmm.20221219.602DOI Listing

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