Crude extracts of Bombyx mori brains can provoke adult development when injected into brain-removed dormant pupae of Bombyx mori and Samia Cynthia ricini. From this fact the prothoracicotropic hormone (PTTH) of Bombyx has long been thought to be species-nonspecifically active on Samia. Chemical fractionation of Bombyx brain or head extracts by fractional precipitation with acetone, Sephadex G-50 gel-filtration, and DEAE-Sepharose CL-6B chromatography, however, separated the fractions which activated Bombyx brainless pupae from those which activated Samia. Those results reveal the existence of two species-specific PTTHs.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1440-169X.1983.00593.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Photoperiodic plasticity of pigment-dispersing factor immunoreactive fibers projecting toward prothoracicotropic hormone neurons in flesh fly Sarcophaga similis larvae.
J Comp Physiol A Neuroethol Sens Neural Behav Physiol
January 2025
Graduate School of Science, The University of Osaka, 1-1 Machikaneyama-cho, Toyonaka, Osaka, 560-0043, Japan.
Larvae of the flesh fly, Sarcophaga similis exhibit photoperiodic responses to control pupal diapause. Although the external coincidence model is applicable to S. similis photoperiodism, it remains unknown how the circadian clock system integrates day-length information.
View Article and Find Full Text PDFThe role of neuropeptide prothoracicotropic hormone (PTTH) - Torso in pyriproxyfen-induced larval-pupal abnormal metamorphosis in silkworms.
Pestic Biochem Physiol
November 2024
College of Agriculture, Guangxi University, Nanning, Guangxi 530004, PR China; Guangxi Key Laboratory of Agro-Environment and Agric-Products Safety, National Demonstration Center for Experimental Plant Science Education, College of Agriculture, Guangxi University, Nanning, Guangxi 530004, PR China. Electronic address:
Article Synopsis
- - The neuropeptide prothoracicotropic hormone (PTTH) regulates ecdysone synthesis critical for insect metamorphosis, while pyriproxyfen, a juvenile hormone analogue, disrupts this process in silkworms.
- - RNA-seq analysis revealed 3,774 differentially expressed genes in the prothoracic gland after pyriproxyfen exposure, primarily affecting the MAPK signaling pathway linked to PTTH.
- - Increased PTTH levels were observed, but downstream signaling genes (like torso and ERK) were down-regulated, indicating that pyriproxyfen interferes with metamorphosis by impairing PTTH-Torso signaling.
Neuronal and endocrine mechanisms underlying the circadian gating of eclosion: insights from Drosophila.
Curr Opin Insect Sci
December 2024
Centro Interdisciplinario de Neurociencias de Valparaíso, Universidad de Valparaíso, Valparaíso, Chile; Instituto de Neurociencias de Valparaíso, Universidad de Valparaíso, Valparaíso, Chile. Electronic address:
The circadian rhythm of adult emergence (aka eclosion) of the fruit fly Drosophila is a classic behavioural read-out that served in the first characterisation of the key features of circadian clocks and was also used for the identification of the first clock genes. Rhythmic eclosion requires the central clock in the brain, as well as a peripheral clock in the steroidogenic prothoracic gland. Here, we review recent findings on the timing and neuroendocrine coupling mechanisms of the two clocks.
View Article and Find Full Text PDFA Neuropeptide Signaling Network That Regulates Developmental Timing and Systemic Growth in Drosophila.
J Comp Neurol
October 2024
Department of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, California, USA.
Animals sense chemical cues such as nutritious and noxious stimuli through the chemosensory system and adapt their behavior, physiology, and developmental schedule to the environment. In the Drosophila central nervous system, chemosensory interneurons that produce neuropeptides called Hugin (Hug) peptides receive signals from gustatory receptor neurons and regulate feeding behavior. Because Hug neurons project their axons to the higher brain region within the protocerebrum where dendrites of multiple neurons producing developmentally important neuropeptides are extended, it has been postulated that Hug neurons regulate development through the neuroendocrine system.
View Article and Find Full Text PDFEfficient CRISPR/Cas9-mediated genome editing in the European corn borer, Ostrinia nubilalis.
Insect Mol Biol
February 2025
Department of Biology, Tufts University, Medford, Massachusetts, USA.
The European corn borer (Ostrinia nubilalis) is an agricultural pest and burgeoning model for research on speciation, seasonal adaptation and insect resistance management. Although previous work in O. nubilalis has identified genes associated with differences in life cycle, reproduction, and resistance to Bt toxins, the general lack of a robust gene-editing protocol for O.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!