The condensate-forming ability of transcription factors (TFs) has received considerable attention, although how condensates function in transcription remains unclear. In this issue of Developmental Cell, Wang et al. show that target DNA and transcriptional regulators work as soap-like surfactants to adsorb on condensates, affecting the activities of transcriptional condensates.
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| http://dx.doi.org/10.1016/j.devcel.2023.05.002 | DOI Listing |
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