Metabolism: How a eukaryote adapted to life without respiration.

Curr Biol

VIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, 3001, Belgium; CMPG Laboratory of Genetics and Genomics, Department M2S, KU Leuven, Leuven, 3001, Belgium. Electronic address:

Published: June 2023

A new study finds that Schizosaccharomyces japonicus, a eukaryote that lost the ability to respire, modified its central carbon metabolism to maintain efficient ATP production, cofactor regeneration, and amino-acid production. This remarkable metabolic flexibility opens new avenues towards applications.

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Source
http://dx.doi.org/10.1016/j.cub.2023.05.002DOI Listing

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