How to initiate tissue regeneration by generating mutually exclusive cell states.

PLoS Biol

Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, Colorado, United States of America.

Published: June 2023

A healing wound is made of cells that paused proliferation and secrete mitogenic factors and cells that proliferate to replace those lost to cell death. A new study in PLOS Biology describes how 2 conserved signaling pathways could repress each other to create these mutually exclusive cell states.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243753PMC
http://dx.doi.org/10.1371/journal.pbio.3002155DOI Listing

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