AI Article Synopsis
- Adrenal infarction is a rare condition where parts of the adrenal glands get damaged, and it's often caused by blood conditions or diseases.
- An 81-year-old man came to the hospital with severe back pain, and doctors found he had this condition linked to a blood disease called MDS/MPN.
- This case is special because it's the first time someone has had adrenal infarction twice, and it shows how important it is to investigate the reasons behind these health issues.
Article Abstract
Background: Bilateral adrenal infarction is rare and only a small number of cases have been reported so far. Adrenal infarction is usually caused by thrombophilia or a hypercoagulable state, such as antiphospholipid antibody syndrome, pregnancy, and coronavirus disease 2019. However, adrenal infarction with myelodysplastic/myeloproliferative neoplasm (MDS/MPN) has not been reported.
Case Presentation: An 81-year-old man with a sudden severe bilateral backache presented to our hospital. Contrast-enhanced computed tomography (CT) led to the diagnosis of bilateral adrenal infarction. Previously reported causes of adrenal infarction were all excluded and a diagnosis of MDS/MPN-unclassifiable (MDS/MPN-U) was reached, which was considered to be attributed to adrenal infarction. He developed a relapse of bilateral adrenal infarction, and aspirin administration was initiated. Partial primary adrenal insufficiency was suspected as the serum adrenocorticotropic hormone level was persistently high after the second bilateral adrenal infarction.
Conclusion: This is the first case of bilateral adrenal infarction with MDS/MPN-U encountered. MDS/MPN has the clinical characteristics of MPN. It is reasonable to assume that MDS/MPN-U may have influenced bilateral adrenal infarction development, considering the absence of thrombosis history and a current comorbid hypercoagulable disease. This is also the first case of recurrent bilateral adrenal infarction. It is important to carefully investigate the underlying cause of adrenal infarction once adrenal infarction is diagnosed, as well as to assess adrenocortical function.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240100 | PMC |
| http://dx.doi.org/10.1186/s12902-023-01384-5 | DOI Listing |
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