Hydrogels is a hydrophilic, cross-linked polymer of three-dimensional network structures. The application of hydrogels prepared from a single polymer in the biomedical field has many drawbacks. The functional blend of polyvinyl alcohol and chitosan allows hydrogels to have better and more desirable properties than those produced from a single polymer, which is a good biomaterial for development and design. In this paper, we have reviewed the progress in the application of polyvinyl alcohol/chitosan composite hydrogels in various medical fields, the different cross-linking agents and cross-linking methods, and the research progress in the optimization of composite hydrogels for their subsequent wide range of biomedical applications.
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http://dx.doi.org/10.1016/j.ijbiomac.2023.125192 | DOI Listing |
Int J Biol Macromol
January 2025
"Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, 41 A Gr. Ghica Voda Alley, 700487, Iasi, Romania. Electronic address:
Conductive hydrogels are an appealing class of "smart" materials with great application potential, as they combine the stimuli-responsiveness of hydrogels with the conductivity of magnetic fillers. However, fabricating multifunctional conductive hydrogels that simultaneously exhibit conductivity, self-healing, adhesiveness, and anti-freezing properties remains a significant challenge. To address this issue, we introduce here a freeze-thawing approach to develop versatile, multiresponsive composite cryogels able to preserve their features under low-temperature conditions.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
State Key Lab for Hubei New Textile Materials and Advanced Processing Technology, College of Materials Science & Engineering, College of Textile Science & Engineering, Wuhan Textile University, 430200 Wuhan, China. Electronic address:
Cellulose nanofibers (CNFs) have gained increasing attention due to their robust mechanical properties, favorable biocompatibility, and facile surface modification. However, green and recyclable CNF production remains challenging. Herein, a green, low-cost and room-temperature strategy was developed to exfoliate CNFs using deep eutectic solvents.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Statistics, Imam Khomeini International University, Qazvin, Iran.
Determination of hydrogen peroxide (HO) is of great importance in many systems for controlling the quality of products, food safety, and medical diagnostics. In this work, a highly sensitive photoluminescence film sensor was synthesized based on chitosan (CS), polyvinyl alcohol (PVA), and terephthalic acid (TPA), in the presence of copper (II) ions for determination of hydrogen peroxide. TPA was used as a sensitive probe for detection of hydroxyl radicals produced in a photo-Fenton-like process.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawla II Av., 31-864 Krakow, Poland.
Hydrogels are three-dimensional polymeric matrices capable of absorbing significant amounts of water or biological fluids, making them promising candidates for biomedical applications such as drug delivery and wound healing. In this study, novel hydrogels were synthesized using a photopolymerization method and modified with cisplatin-loaded protein carriers, as well as natural extracts of nettle () and chamomile ( L.).
View Article and Find Full Text PDFJ Biomed Mater Res A
January 2025
Biomedical and Chemical Engineering and BioInspired Syracuse: Institute for Material and Living Systems, Syracuse University, Syracuse, New York, USA.
Chronic wounds present a major healthcare challenge around the world, and significant hurdles remain in their effective treatment due to limitations in accessible treatment options. Mesenchymal stem cells (MSCs) with multifunctional differentiation and modulatory properties have been delivered to chronic wounds to enhance closure but have limited engraftment when delivered without a scaffold. In this study, hybrid porous hydrogel foams composed of modified polyvinyl alcohol and gelatin were developed that are suitable for rapid and facile MSC encapsulation, fully degradable, and supportive of wound healing.
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