Ascites syndrome occurs in growing broiler chickens in all parts of the world, which is one of the important causes of losses in many flocks, and its prevalence has been seen mostly in meat herds. The most important factor in the occurrence of ascites syndrome is the lack of oxygen in body tissues (hypoxia). Increasing the growth rate requires increasing the volume of blood flowing in the body to deliver nutrients to the organs and expel gases and metabolic products. Therefore, this experiment was conducted to compare the effect of peppermint extract and probiotics on the biochemical factors of the blood of chickens caused by ascites. The treatments were divided into 8 groups of 7 male chickens with 3 repetitions in each group at 21 days. The experimental treatments included control and treatments of peppermint, probiotic, peppermint and probiotic, induced ascites, induced ascites and peppermint, induced ascites and probiotics, induced ascites and peppermint and probiotics. At the end of 42 days, the blood factors of uric acid, triglyceride, glucose, cholesterol, ALT, ALP, and AST were measured by blood sampling. The experimental treatments significantly affected the investigated traits (<0.05). Considering that in the treatment of induced ascites+ peppermint compared to the treatment of induced ascites, weight gain was significant, and in the blood factors of cholesterol, triglyceride, uric acid, glucose, and functional liver enzymes including ALT, AST, ALP recorded a significant decrease. Therefore, the effectiveness of peppermint extract in improving induced ascites in chickens was determined. Peppermint extract had a positive effect on induced ascites and improved the performance indicators of broiler chickens, and this extract can be used as a preventive of ascites.
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http://dx.doi.org/10.22092/ARI.2022.360090.2549 | DOI Listing |
Heliyon
January 2025
DBT-BUILDER National Laboratory, Department of Life Sciences, Pachhunga University College, Aizawl, 796001, Mizoram, India.
Purkay. is a lesser-known species of holly (family Aquifoliaceae) that is endemic to Northeast India. Designated as critically endangered, the plant is used in the treatments of bacterial infections, cancer, intestinal helminthiasis, tuberculosis, and viral infections.
View Article and Find Full Text PDFMicrob Pathog
January 2025
São Paulo State University (UNESP), Aquaculture Center of UNESP, Laboratory of Microbiology and Parasitology of Aquatic Organisms, Jaboticabal, São Paulo, Brazil, 14.884-900; Graduate Program in Agricultural and Livestock Microbiology, São Paulo State University (UNESP), School of Agricultural and Veterinarian Sciences, Jaboticabal, São Paulo, Brazil, 14884-900. Electronic address:
Lactococcus petauri is an emerging pathogen causing piscine lactococcosis in various aquatic species. This disease has been increasingly reported as a cause of mortality in aquaculture. Due to the indiscriminate use of antimicrobials and to promote viable alternatives for their replacement, bioactive peptides with antimicrobial properties can be explored as tools against bacterial infections.
View Article and Find Full Text PDFIn our efforts to enhance sensitivity to PARP inhibitors, we identified clofarabine (CLF) as a potential therapy for drug-resistant ovarian cancer and nuclear trafficking of Cathepsin L (CTSL) as a treatment- responsive biomarker. Using PARP inhibitor-sensitive and -resistant OC cell lines, ex vivo cultures of patient-derived ovarian ascites (OVA), primary ovarian tumors, and xenografts (PDX), we found that CLF monotherapy induces nuclear CTSL (nCTSL) in CLF-responsive cells (CLF-r) and sensitizes them to PARP inhibitors olaparib and rucaparib. In CLF non-responsive cells (CLF-nr), a combination of CLF with olaparib is necessary for nCTSL trafficking and synergy.
View Article and Find Full Text PDFPharmaceuticals (Basel)
December 2024
Post Graduate Program in Structural and Functional Biology, Paulista School of Medicine (UNIFESP-EPM), Federal University of São Paulo, São Paulo 04023-062, SP, Brazil.
is traditionally known for its medicinal properties. Objectives: Here, we investigated the effects of crude extract (CE) and ethyl acetate fraction (EAF) obtained from leaves on the ascitic (EA) and solid (ES) forms of Ehrlich tumors. : Induced and uninduced BALB/c mice were treated intramuscularly, for 7 or 14 days, with saline solution or CE and EAF, both at a 10% concentration, based on in vitro cytotoxicity assessment.
View Article and Find Full Text PDFJ Hepatocell Carcinoma
January 2025
Department of Interventional and Vascular Surgery, Peking University First Hospital, Beijing, People's Republic of China.
Purpose: Portal vein tumor thrombus (PVTT)-related severe symptomatic portal hypertension (SPH) leads to a poor prognosis in patients with advanced hepatocellular carcinoma (HCC). Traditional transjugular intrahepatic portosystemic shunt (TIPS) using covered plus bare stent can effectively relieve SPH, however, the bare segment is susceptible to obstruction due to PVTT invasion. This study aimed to evaluate the safety and efficacy of fully covered stent-TIPS (FCS-TIPS) for treatment of PVTT-related SPH in advanced HCC patients.
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