An expeditious and regioselective approach towards the construction of a spiro-chroman motif is described. Quinone methides underwent a PTSA catalyzed annulation with 2-benzylidene dithiolanes to afford spiro-chroman dithiolanes in high yields. The synthetic versatility of the dithiolane motif was demonstrated by converting the adduct to coumarin, 3,4-dihydrocoumarin and chroman derivatives.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d3ob00583f | DOI Listing |
Publication Analysis
Top Keywords
quinone methides
8
2-benzylidene dithiolanes
8
annulation quinone
4
methides 2-benzylidene
4
dithiolanes
4
dithiolanes synthesis
4
synthesis spirochroman
4
spirochroman dithiolanes
4
dithiolanes expeditious
4
expeditious regioselective
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!