AI Article Synopsis
- Non-functional pituitary carcinoma is a rare type of tumor that spreads without causing hormonal overproduction, and few cases have been documented.
- A case study highlighted a 48-year-old woman who experienced spinal pain and was found to have non-functional pituitary carcinoma after surgery and examination.
- Distinguishing between non-functional pituitary adenomas and carcinomas is difficult, and managing these tumors usually requires a combination of surgery, chemotherapy, and radiotherapy.
Article Abstract
Introduction And Importance: Non-functional pituitary carcinoma is a rare neuroendocrine tumor. It is characterized by the presence of cerebrospinal or distant metastasis of an adenohypophysis tumor without any hypersecretion. Only a few cases of non-functional pituitary carcinomas have been reported in the literature.
Case Presentation: In this paper, we report the case of a 48-year-old female patient who presented with spinal pain and a mass facing the second thoracic vertebrae. Spinal magnetic resonance imaging (MRI) revealed the presence of pituitary and bilateral adrenal incidentalomas. The patient was operated and the histopathological examination of the specimen revealed a non-functional pituitary carcinoma variety "Null Cell".
Discussion And Conclusion: There are no clinical, biological, or radiological characteristics that reliably differentiate between non-functional pituitary adenoma and non-functional pituitary carcinoma. Management remains a challenge for clinicians and neurosurgeons. A combination of surgery, chemotherapy, and radiotherapy seems necessary to achieve tumor control.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250797 | PMC |
| http://dx.doi.org/10.1016/j.ijscr.2023.108376 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!