AI Article Synopsis
- A study was conducted to assess how propofol sedation affects sleep quality after gastrointestinal endoscopy in 880 patients.
- The researchers measured sleep quality using specific scores before and after the procedure, finding a significant decline in sleep quality for those who received sedation in the short term (1-7 days post-GE).
- By 3 weeks post-procedure, sleep quality for both the sedation and control groups returned to baseline levels, indicating no long-term effects from the sedation.
Article Abstract
Purpose: Some patients experience sleep disturbances after endoscopy performed under sedation. This study aimed to evaluate the effects of propofol on sleep quality after gastrointestinal endoscopy (GE).
Design: This study was a prospective cohort study.
Methods: This study enrolled 880 patients who underwent GE. Patients who chose to undergo GE under sedation received intravenous propofol, whereas the control group did not. The Pittsburgh Sleep Quality Index (PSQI) was measured before GE (PSQI-1) and 3 weeks (PSQI-2) after GE. The Groningen Sleep Score Scale (GSQS) was used before GE (GSQS-1) and 1 (GSQS-2) and 7 days (GSQS-3) after GE.
Findings: There was a significant increase in GSQS scores from baseline to days 1 and 7 after GE (GSQS-2 vs GSQS-1, P < .001, GSQS-3 vs GSQS-1, P = .008). However, no significant changes were observed in the control group (GSQS-2 vs GSQS-1, P = .38, GSQS-3 vs GSQS-1, P = .66). On day 21, there were no significant changes in the baseline PSQI scores over time in either group (sedation group, P = .96; control group, P = .95).
Conclusions: GE with propofol sedation negatively affected sleep quality for 7 days after GE but not 3 weeks after GE.
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| http://dx.doi.org/10.1016/j.jopan.2023.02.001 | DOI Listing |
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