Objectives: Describe the radiographic features of the different forms of extrauterine leiomyomatosis.
Conclusions: Leiomyomas with a rare growth pattern occur most often in women of reproductive age and with a history of hysterectomy. Extrauterine leiomyomas present a greater diagnostic challenge because they may mimic malignancies, and serious diagnostic errors may result.
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http://dx.doi.org/10.1016/j.rxeng.2023.01.004 | DOI Listing |
Adv Anat Pathol
January 2025
Department of Pathology, University of Michigan-Michigan Medicine, Ann Arbor, MI.
Uterine smooth muscle neoplasms are a biologically and clinically heterogeneous group of tumors. Morphology is the cornerstone of pathologic diagnosis of these tumors, and most are readily classified as benign or malignant on the basis of routine histologic examination. However, rare subsets-including intravenous leiomyomatosis, benign metastasizing leiomyoma, and disseminated peritoneal leiomyomatosis-have a capacity for extrauterine spread despite benign cytomorphology.
View Article and Find Full Text PDFQatar Med J
September 2024
Obstetrics and Gynaecology Department, Federal Medical Centre Keffi, Keffi, Nigeria.
Indian J Radiol Imaging
October 2024
Department of Radiodiagnosis, St John's Medical College and Hospital, Bangalore, Karnataka, India.
Disseminated peritoneal leiomyomatosis is a benign condition characterized by multiple extrauterine leiomyomas in various locations such as the peritoneum, mesentery, abdominal wall, and pelvis. This is typically observed following laparoscopic myomectomy and is an extremely rare disease, with only a limited number of cases reported thus far. It primarily affects women in their reproductive age group and is believed to be associated with ovarian secretions.
View Article and Find Full Text PDFInt J Surg Pathol
February 2025
Department of Pathology, University of Nebraska Medical Center, Omaha, NE, USA.
Background: The occurrence of fumarate hydratase-deficient leiomyoma of the abdominal wall is exceptionally rare.
Case Presentation: A 50-year-old female patient with a past medical history of fumarate hydratase-deficient uterine leiomyoma presented with a left lower quadrant abdominal mass that has been present for the past 2 years. An ultrasound revealed a 3.
Medicine (Baltimore)
January 2024
Department of Pathology, Dujiangyan Maternity and Child Health Hospital, Chengdu, Sichuan, China.
Rationale: Intravascular/intravenous leiomyomatosis (IVL) is a peculiar variant of uterine leiomyoma that is classified as a histologically benign smooth muscle tumor with a biological behavior similar to that of a malignant tumor. It is characterized by the proliferation of leiomyomas spreading along the uterine and extrauterine venous circulation.
Patient Concerns: Herein, we present 2 cases of IVL who had completely different clinical manifestations to stress the need for constant vigilance of IVL diagnosis and the understanding of uterine leiomyoma heterogenicity.
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