In this issue of Molecular Cell, Abril-Garrido et al. used cryo-EM to uncover that the +1 nucleosome inhibits transcription by interfering with the function of the TFIIH translocase via mechanisms that depend on its position relative to the transcription start site.
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| http://dx.doi.org/10.1016/j.molcel.2023.05.003 | DOI Listing |
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