Potentially deadly drug rashes include Stevens-Johnson syndrome/toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, and drug-induced vasculitis. Differentiating them can be a challenge. Factors to consider include timing of rash to drug exposure, rash distribution and clinical appearance, and the presence of systemic features such as mucosal involvement, organ failure, or eosinophilia. Various scoring systems aid in the diagnosis, but skin biopsy is the gold standard. Prompt identification and withdrawal of the suspected offending agent are the crucial first steps in management.

Download full-text PDF

Source
http://dx.doi.org/10.3949/ccjm.90a.22043DOI Listing

Publication Analysis

Top Keywords

deadly drug
8
drug rashes
8
rashes early
4
early recognition
4
recognition multidisciplinary
4
multidisciplinary care
4
care deadly
4
rashes include
4
include stevens-johnson
4
stevens-johnson syndrome/toxic
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!