AI Article Synopsis
- A 77-year-old Japanese woman was diagnosed with sarcoidosis after presenting with mediastinal lymphadenopathy and uveitis.
- * Researchers used Sanger sequencing to analyze the bacterial flora from her biopsied mediastinal lymph nodes and found Streptococcus gordonii and Cutibacterium acnes.
- * This case report is significant as it is the first to document these specific bacteria in the mediastinal lymph nodes of a sarcoidosis patient using the Sanger method.
Article Abstract
A 77-year-old Japanese woman with mediastinal lymphadenopathy and uveitis was diagnosed with sarcoidosis. The bacterial flora in biopsied samples from mediastinal lymph nodes was analyzed using a clone library method with Sanger sequencing of the 16S rRNA gene, and Streptococcus gordonii (52 of 71 clones) and Cutibacterium acnes (19 of 71 clones) were detected. No previous study has conducted a bacterial floral analysis using the Sanger method for the mediastinal lymph node in sarcoidosis, making this case report the first to document the presence of S. gordonii and C. acnes in the mediastinal lymph node of a patient with sarcoidosis.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10864086 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.1887-23 | DOI Listing |
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